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Fig. 7 | BMC Musculoskeletal Disorders

Fig. 7

From: Effects of osteochondral defect size on cartilage regeneration using a double-network hydrogel

Fig. 7

The O’Discoll score for quantitative histological evaluation. At 2 weeks, there were no statistically significant differences in the score in any of the three groups. At 4weeks, the scores in G-II and III with DN gel were significantly higher than in the untreated controls (p = 0.0040, p = 0.0001, respectively). The scores in the G-I untreated controls were significantly higher than those in the G-II and III untreated controls (p = 0.0212, p < 0.0001, respectively). At 12 weeks, the scores in G-II and III with DN gel were significantly higher than in the untreated controls (p = 0.0008, p = 0.0294, respectively). The scores in G-I and II with DN gel were significantly higher than those in G-III with DN gel (p = 0.0063, p = 0.0280, respectively). The scores in the G-I untreated controls were significantly higher than those in the G-II and III untreated controls (p = 0.0421, p = 0.0001, respectively). *The scores in G-III with DN gel at 12 weeks were significantly lower than those in G-III with DN gel at 4 weeks. (p = 0.0057)

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