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Table 3 Overview of significant and nonsignificant risk factors in meta-analyses

From: Restriction in lateral bending range of motion, lumbar lordosis, and hamstring flexibility predicts the development of low back pain: a systematic review of prospective cohort studies

Risk Factor

Study

Measurement technique

Effect size (95% CI)

Weight

Lateral flexion range of motion (ROM)

Adams et al [29]

Equipment: 3Space Isotrak device

Method: Sensors on sacrum and L1 spinous process measured degree change between upright standing and max lateral flexion

0.50 (0.29-0.86)

65.06

Kujala et al [35]

Equipment: Tape measure

Methods: Difference between middle finger position on ipsilateral thigh to most distal position of middle finger achieved in max lateral flexion

0.49 (0.14-1.74)

17.71

Van Nieuwenhuyse et al [38]

Equipment: Tape measure

Methods: Difference between middle finger position on ipsilateral thigh to most distal position of middle finger achieved in max lateral flexion

0.17 (0.05-0.61)

17.23

Overall effect size (I-squared = 15.9%, p = 0.304)

0.41 (0.24-0.73, p = 0.002)

100

Lumbar lordosis

Adams et al [29]

Equipment: 3Space Isotrak device

Method: Sensors on sacrum and L1 spinous process measured degrees of lordosis in upright standing

0.56 (0.38-0.83)

35.48

Milgrom et al [37]

Equipment: Cybex (EDI 320) inclinometer

Method: Inclinometer place over spinous process of L4 and lordosis angle measured relative to horizontal

0.88 (0.48-1.62)

18.37

Nissinen et al [39]

Equipment: Spinal pantograph

Method: Spinal pantograph used to measure lordosis angle in an upright standing

0.84 (0.61-1.16)

46.15

Overall effect size (I-squared = 29.7%, p = 0.241)

0.73 (0.55-0.98, p = 0.034)

100

Hamstring flexibility

Feldman et al [31]

Equipment: Goniometer

Method: Supine position with hip at 90°, ipsilateral knee extended from 90° of flexion

0.96 (0.94-0.98)

99.92

 

Kujala et al [35]

Equipment: Hydrogoniometer

Method: Straight leg raise

0.70 (0.20-2.45)

0.04

 

Van Nieuwenhuyse et al [38]

Equipment: Inclinometer

Method: Straight leg raise

1.00 (0.31-3.2)

0.04

 

Overall effect size (I-squared = 0%, p = 0.883)

0.96 (0.94-0.98, p = 0.001)

100

Back muscle strength

Biering-Sorensen et al [30]

Equipment: Strain gauge dynamometer

Methods: Device attached to shoulders of participant and the MVC of 3 attempts of extension in upright standing

1.49 (0.70-3.16)

71.35

Gibbons et al [32]

Equipment: not clear

Methods: Max isokinetic strength from forward flexion to upright standing

1.81 (0.55-5.93)

28.65

Overall effect size (I-squared = 0%, p = 0.788)

1.58 (0.83-2.97, p = 0.160)

100

Back muscle fatigability

Adams et al [29]

Equipment: Stopwatch

Methods: Biering-Sorensen test

0.80 (0.60-1.07)

42.59

Biering-Sorensen et al [30]

Equipment: Stopwatch

Methods: Biering-Sorensen test

0.42 (0.16-1.14)

16.57

Gibbons et al [32]

Equipment: Stopwatch

Methods: Biering-Sorensen test

0.85 (0.26-2.77)

12.97

Kujala et al [35]

Equipment: Stopwatch

Methods: Biering-Sorensen test

1.87 (0.53-6.56)

11.80

Luoto et al [36]

Equipment: Stopwatch

Methods: Biering-Sorensen test

0.29 (0.11-0.81)

16.06

Overall effect size (I-squared = 41.2%, p = 0.147)

0.68 (0.42-1.12 p = 0.160)

100

Lumbar flexion range of motion (ROM)

Adams et al [29]

Equipment: 3Space Isotrak device

Method: Sensors on sacrum and L1 spinous process measured degree change between upright standing and max forward flexion sitting with legs extended

1.25 (0.94-1.67)

50.92

Biering-Sorensen et al [30]

Equipment: Tape measure

Method: Modified Schober

2.59 (1.23-5.46)

19.98

Feldman et al [31]

Equipment: Tape measure

Method: Schober

0.93 (0.45-1.93)

20.43

Kujala et al [35]

Equipment: Tape measure

Method: Modified Schober

0.88 (0.25-3.07)

8.67

Overall effect size (I-squared = 34%, p = 0.209)

1.32 (0.89-1.96, p = 0.167)

100

Lumbar extension ROM

Adams et al [29]

Equipment: 3Space Isotrak device

Method: Sensors on sacrum and L1 spinous process measured degree change between upright standing and max extension in prone position

0.95 (0.67-1.34)

45.69

Kujala et al [35]

Equipment: Draughtsman’s flexible curve

Method: Devices placed on spinous process of S2, L4, and T12 in prone position with max extension. Curve traced on paper then angle in degrees measured.

1.19 (0.34-4.14)

22.76

Van Nieuwenhuyse et al [38]

Equipment: none

Method: passive extension of lower back measured as presence or absence of pain

0.29 (0.12-0.70)

31.55

Overall effect size (I-squared = 68.7%, p = 0.041)

0.69 (0.31-1.55, p = 0.367)

100

Isometric abdominal strength

Biering-Sorensen et al [30] 0

Equipment: Strain gauge dynamometer

Methods: Device attached to shoulders of participant and the MVC of 3 attempts of flexion in upright standing

1.20 (0.56-2.53)

16.62

Feldman et al [31]

Equipment: Hand held myometer

Methods: Sit-up, stop midway then resistance applied to the sternum. Max force that participant could hold in that position recorded

0.96 (0.69-1.34)

83.38

Overall effect size (I-squared = 0%, p = 0.602)

1.00 (0.73-1.35, p = 0.976)

100

Fingertip to floor distance

Biering-Sorensen et al [30]

Equipment: Tape measure

Method: Distance from tips of the middle fingers to the ground during max forward bending with feet together and knees extended

0.96 (0.40-2.28)

0.13

Feldman et al [31]

Equipment: Sit and reach box

Method: Sitting with hips flexed and knees extended

1.00 (0.97-1.03)

99.53

Kujala et al [35]

Equipment: Tape measure

Method: Distance from tips of the middle fingers to the ground during max forward bending with feet together and knees extended

2.65 (0.75-9.37)

0.06

Van Nieuwenhuyse et al [38]

Equipment: Tape measure

Method: Distance from tips of the middle fingers to the ground during max forward bending with feet together and knees extended

1.00 (0.55-1.81)

0.28

 

Overall effect size (I-squared = 0%, p = 0.515)

1.00 (0.97-1.03, p = 0.973)

100

Quadriceps flexibility

Feldman et al [31]

Equipment: Goniometer

Method: Degrees of knee flexion in a prone position

1.02 (0.92-1.13)

62.13

Kanchanomai et al [33]

Equipment: Goniometer

Method: Stationary arm of device aligned with the lateral midline of the thigh, fulcrum is placed over the lateral epicondyle of the femur and the moving arm is aligned with the lateral midline of the fibula. Smaller degrees of knee flexion equated to tighter quadriceps

1.71 (1.03-2.84)

37.87

Overall effect size (I-squared = 73.9%, p = 0.050)

1.24 (0.76-2.03, p = 0.389)

100

Erector spinae CSA

Fortin et al [40]

Equipment: 1.5 Tesla Magnetom SP 4000 magnetic resonance imager

Method: T2-weighted techniques at L3-4 and L5-S1

-0.09 (-0.48-0.31)

27.25

Gibbons et al [32]

Equipment: 1.5 tesla Magnetom magnetic resonance imager

Method: Slice thickness was 3 mm and gaps between the slices 0.3 mm at the L3-4 level.

0.00 (-0.65-0.65)

72.75

Overall effect size (I-squared = 0%, p = 0.823)

-0.06 (-0.40-0.28, p = 0.722)

100

Quadratus lumborum CSA

Gibbons et al [32]

Equipment: 1.5 tesla Magnetom magnetic resonance imager

Method: Slice thickness was 3 mm and gaps between the slices 0.3 mm at the L3-4 level.

2.96 (0.89-9.86)

82.85

Kountouris et al [34]

Equipment: MRI and imaging software

Method: Axial MR images measured at L2 and L4 levels

0.55 (0.03-10.37)

17.15

Overall effect size (I-squared = 8%, p = 0.297)

2.22 (0.63-7.74, p = 0.212)

100

  1. MVC max voluntary contraction, CSA cross sectional area, MRI magnetic resonance imaging