Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity

Fenton, Sally A. M.; Veldhuijzen van Zanten, Jet J. C. S.; Kitas, George D.; Duda, Joan L.; Rouse, Peter C.; Yu, Chen-an; Metsios, George S.

doi:10.1186/s12891-017-1473-9

Table 1 Descriptive statistics for the total sample and sample stratified by gender

From: Sedentary behaviour is associated with increased long-term cardiovascular risk in patients with rheumatoid arthritis independently of moderate-to-vigorous physical activity

	Male (N = 20)	Female (N = 41)	Total (N = 61)
Age (years)	58.85 ± 9.44	53.00 ± 13.28	54.92 ± 12.39
Height (m)	1.73 ± 0.10	1.63 ± 0.06	1.66 ± 0.09
Weight (kg)	78.13 ± 10.33	76.81 ± 19.42	77.23 ± 16.94
Ethnicity (% Caucasian)	31.1	54.1	85.2
RA duration (years from diagnosis)	5.05 ± 5.44	7.97 ± 10.34	6.96 ± 9.01
Accelerometer data
Average valid wear time (hours/day)	12.99 ± 0.74	13.12 ± 0.77	13.08 ± 0.76
Sedentary time (min/day)	505.40 ± 71.45	493.52 ± 67.24	497.42 ± 68.28
^a LPA (min/day)	251.14 ± 71.79	278.23 ± 67.22	269.35 ± 69.35
^a MVPA (min/day)	22.65 ± 22.53	15.70 ± 13.77	17.98 ± 17.26
Sedentary behaviour patterns
Number of Sbreaks (average/day)	79.59 ± 16.89	86.52 ± 11.94	84.32 ± 14.02
Number of Sbouts ≥ 20 min (average/day)	6.37 ± 2.41	5.45 ± 1.91	5.75 ± 2.11
Average time per Sbouts ≥ 20 (min)	31.08 ± 2.07	30.64 ± 2.75	30.78 ± 2.54
10 year risk of CVD
Q-risk (% risk of 10 year CVD)	24.14 ± 14.82	12.54 ± 11.05	16.33 ± 13.45^**
Self-reported smoking status (% smokers)	3.65	3.65	7.3
Diabetic status (% diabetic)	1.8	5.5	7.3
Presence of kidney disease (% yes)	0	0	0
Family history of heart disease (% yes)	118.1	36.4	54.5
Individual CVD risk factors
^a CRP (mg/L)	6.72 ± 8.12	7.66 ± 9.58	7.35 ± 9.09
^a ESR (mm/h)	10.00 ± 8.12	16.55 ± 16.50	14.37 ± 14.52
Fibrinogen (g/L)	4.64 ± 0.90	4.60 ± 1.20	4.62 ± 1.10
Total cholesterol (mmol/L)	4.77 ± 0.70	5.01 ± 1.09	4.93 ± 0.98
^a HDL-C (mmol/L)	1.26 ± 0.32	1.54 ± 0.36	1.45 ± 0.37^**
^a LDL-C (mmol/L)	2.88 ± 0.80	2.99 ± 0.93	2.95 ± 0.88
^a Triglycerides (mmol/L)	1.39 ± 0.83	1.05 ± 0.52	1.16 ± 0.65
Syst-BP (mm HG)	138.07 ± 19.45	132.32 ± 16.98	134.08 ± 17.77
Diast-BP (mm HG)	83.13 ± 9.96	79.18 ± 8.58	80.39 ± 9.11
^a Plasma insulin (mmol/L)	57.35 ± 26.68	59.32 ± 55.82	58.67 ± 47.99
^a Plasma glucose (mmol/L)	4.65 ± 0.38	4.80 ± 1.21	4.75 ± 1.01
^a HOMA status	1.70 ± 0.82	2.11 ± 3.34	1.97 ± 2.77
Functional Disability
^a HAQ	1.74 ± 0.63	1.64 ± 0.56	1.67 ± 0.58

Note: Gender differences indicated as ** = p < .01. Data pertaining to Q-risk-score, ESR, LDL-C, blood pressure and functional disability (HAQ) were available for participants (N = (male, female)) as follows; Q-risk-score, N = 55 (18, 37), ESR, N = 60 (20, 40), LDL-C, N = 60 (19, 41) functional disability, N = 60 (20, 40). Data for Q-risk variables (e.g., smoking status) are reported for participants who have computed Q-risk score (N = 55)
^aindicates non-normally distributed data that has been log transformed for inclusion parametric statistical tests. RA rheumatoid arthritis, LPA light physical activity, MVPA moderate-to-vigorous physical activity, Sbreaks sedentary breaks, Sbouts sedentary bouts, CVD cardiovascular disease, Q-risk Q-risk-score, CRP C-reactive protein, ESR erythrocyte sedimentation rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, Syst-BP systolic blood pressure, Diast-BP diastolic blood pressure, HOMA homeostatic model assessment, HAQ Health Assessment Questionnaire

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ISSN: 1471-2474

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