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Table 1 Genotypic and allelic frequency of MUTYH-437 (rs3219463) genetic polymorphism in the RA patients and controls

From: Polymorphism and protein expression of MUTYH gene for risk of rheumatoid arthritis

 

RA patient

Control

OR (95% CI)

p value

MUTYH-437 (rs3219463)

n = 368 (%)

n = 364 (%)

  

AA

54 (14.7)

47 (12.9)

1.80 (1.14-2.84)

6E-06 *

AG

204 (55.4)

145 (39.8)

2.20 (1.60-3.03)

GG

110 (29.9)

172 (47.3)

Ref

Allelic frequency

 Allele A

312 (42.4)

239 (32.8)

1.51 (1.22-1.86)

0.0002 *

 Allele G

424 (57.6)

489 (67.2)

Ref

  1. CI confidence interval, OR odds ratio
  2. * Statistically significant