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Table 3 Values obtained at high-intensity exercise performance in women with fibromyalgia (FM) (n = 22) and the healthy reference group (n = 27). Mean value and SD of differences (∆), p-value for within-group differences as well as for between- group differences are presented

From: Acute effects of physical exercise on the serum insulin-like growth factor system in women with fibromyalgia

High-intensity exercise

 

Women with FM, n = 22

Healthy reference group, n = 27

Between-group differences

 

0 min

15 min–0 min

0 min

15 min–0 min

0 min

Change 0–15 min

 

Mean ± sd

∆ mean ± sd

p-value

Mean ± sd

∆ mean ± sd

p-value

p-value

p-value

S-IGF-1 (ng/ml)

195 ± 60

11 ± 15

<0.001

181 ± 66

19 ± 22

<0.001

0.244

0.560

Free IGF-1 (ng/ml)

4.7 ± 2.6

−0.42 ± 0.48

0.014

4.7 ± 3.2

−0.56 ± 0.76

<0.001

0.755

0.843

S-IGFBP3 (ng/ml)

556 ± 75

25 ± 37

0.009

614 ± 91

25 ± 41

0.008

0.037

0.942

sCRP μg/ml)

2.1 ± 2.4

0.06 ± 0.16

0.002

0.70 ± 0.77

0.04 ± 0.06

<0.001

0.001

0.119

IL-8 (pg/ml)

7.5 ± 3.0

0.7 ± 2.9

0.545

9.7 ± 4.2

−0.2 ± 1.9

0.673

0.107

0.565

Pain (0–100, mm)

46 ± 24.4

−4.0 ± 16.1

0.291

2.4 ± 7.4

0 ± 3.6

0.878

<0.001

0.139

Fatigue in legs (0–100 mm)

31 ± 21

28 ± 20

<0.001

1.2 ± 3.1

12 ± 13

<0.001

<0.001

0.003

Fatigue global (0–100 mm)

50 ± 24

8.4 ± 19

0.007

3.0 ± 5.3

6.3 ± 10

<0.001

<0.001

0.414

  1. S-IGF-1 serum insulin-like growth factor-1, S-IGFBP3 Insulin-like growth factor binding protein-3, sCRP human high sensitivity C-reactive protein, IL-8 interleukin-8