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Table 3 Values obtained at high-intensity exercise performance in women with fibromyalgia (FM) (n = 22) and the healthy reference group (n = 27). Mean value and SD of differences (∆), p-value for within-group differences as well as for between- group differences are presented

From: Acute effects of physical exercise on the serum insulin-like growth factor system in women with fibromyalgia

High-intensity exercise
  Women with FM, n = 22 Healthy reference group, n = 27 Between-group differences
  0 min 15 min–0 min 0 min 15 min–0 min 0 min Change 0–15 min
  Mean ± sd ∆ mean ± sd p-value Mean ± sd ∆ mean ± sd p-value p-value p-value
S-IGF-1 (ng/ml) 195 ± 60 11 ± 15 <0.001 181 ± 66 19 ± 22 <0.001 0.244 0.560
Free IGF-1 (ng/ml) 4.7 ± 2.6 −0.42 ± 0.48 0.014 4.7 ± 3.2 −0.56 ± 0.76 <0.001 0.755 0.843
S-IGFBP3 (ng/ml) 556 ± 75 25 ± 37 0.009 614 ± 91 25 ± 41 0.008 0.037 0.942
sCRP μg/ml) 2.1 ± 2.4 0.06 ± 0.16 0.002 0.70 ± 0.77 0.04 ± 0.06 <0.001 0.001 0.119
IL-8 (pg/ml) 7.5 ± 3.0 0.7 ± 2.9 0.545 9.7 ± 4.2 −0.2 ± 1.9 0.673 0.107 0.565
Pain (0–100, mm) 46 ± 24.4 −4.0 ± 16.1 0.291 2.4 ± 7.4 0 ± 3.6 0.878 <0.001 0.139
Fatigue in legs (0–100 mm) 31 ± 21 28 ± 20 <0.001 1.2 ± 3.1 12 ± 13 <0.001 <0.001 0.003
Fatigue global (0–100 mm) 50 ± 24 8.4 ± 19 0.007 3.0 ± 5.3 6.3 ± 10 <0.001 <0.001 0.414
  1. S-IGF-1 serum insulin-like growth factor-1, S-IGFBP3 Insulin-like growth factor binding protein-3, sCRP human high sensitivity C-reactive protein, IL-8 interleukin-8
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