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Table 3 Subgroup analysis of patients on anticoagulants

From: A comparative, retrospective study of peri-articular and intra-articular injection of tranexamic acid for the management of postoperative blood loss after total knee arthroplasty

Anticoagulation use or not PAI-N (n = 45) PAI-U (n = 4) P value IAI-N (n = 32) IAI-U (n = 4) P value Control-N (n = 38) Control-U (n = 4) P value P* P**
Drainage volume (mL) 324.7 ± 182.1 327.5 ± 296.0 0.98 299.1 ± 172.7 352.5 ± 148.9 0.56 732.4 ± 289.6 645.0 ± 305.1 0.57 0.00, 0.21,
0.90, 0.90,
0.00, 0.18,
0.00 0.15
Hb drop (g/L) 23.2 ± 8.8 23.5 ± 15.5 0.96 23.9 ± 10.0 28.0 ± 9.8 0.44 32.4 ± 14.0 42.0 ± 18.16 0.21 0.00, 0.24,
0.80, 0.68,
0.00, 0.11,
0.00 0.22
Estimated blood loss (mL) 860.6 ± 343.2 1009.7 ± 150.8 0.40 861.4 ± 457.27 1336.1 ± 337.5 0.06 1486.1 ± 1002.3 1496.5 ± 787.4 0.98 0.00, 0.43,
0.99 0.40,
0.00 0.60,
0.00 0.97
  1. Values are expressed as a mean ± standard deviation
  2. PAI peri-articular injection, IAI intra-articular injection, U anticoagulation used, N anticoagulation not used
  3. P*: Differences (Three groups, PAI-N vs. IAI-N, PAI-N vs. Control-N, IAI-N vs. Control-N) among subgroups of PAI-N, IAI-N, and Control-N
  4. P**: Differences (three groups, PAI-U vs. IAI-U, PAI-U vs. Control-U, IAI-U vs. Control-U) among subgroups of PAI-U, IAI-U, and Control-U