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Table 3 Subgroup analysis of patients on anticoagulants

From: A comparative, retrospective study of peri-articular and intra-articular injection of tranexamic acid for the management of postoperative blood loss after total knee arthroplasty

Anticoagulation use or not

PAI-N (n = 45)

PAI-U (n = 4)

P value

IAI-N (n = 32)

IAI-U (n = 4)

P value

Control-N (n = 38)

Control-U (n = 4)

P value

P*

P**

Drainage volume (mL)

324.7 ± 182.1

327.5 ± 296.0

0.98

299.1 ± 172.7

352.5 ± 148.9

0.56

732.4 ± 289.6

645.0 ± 305.1

0.57

0.00,

0.21,

0.90,

0.90,

0.00,

0.18,

0.00

0.15

Hb drop (g/L)

23.2 ± 8.8

23.5 ± 15.5

0.96

23.9 ± 10.0

28.0 ± 9.8

0.44

32.4 ± 14.0

42.0 ± 18.16

0.21

0.00,

0.24,

0.80,

0.68,

0.00,

0.11,

0.00

0.22

Estimated blood loss (mL)

860.6 ± 343.2

1009.7 ± 150.8

0.40

861.4 ± 457.27

1336.1 ± 337.5

0.06

1486.1 ± 1002.3

1496.5 ± 787.4

0.98

0.00,

0.43,

0.99

0.40,

0.00

0.60,

0.00

0.97

  1. Values are expressed as a mean ± standard deviation
  2. PAI peri-articular injection, IAI intra-articular injection, U anticoagulation used, N anticoagulation not used
  3. P*: Differences (Three groups, PAI-N vs. IAI-N, PAI-N vs. Control-N, IAI-N vs. Control-N) among subgroups of PAI-N, IAI-N, and Control-N
  4. P**: Differences (three groups, PAI-U vs. IAI-U, PAI-U vs. Control-U, IAI-U vs. Control-U) among subgroups of PAI-U, IAI-U, and Control-U