Table 5 Association between selected characteristics and disease severity, according to age at diagnosis

Weight at 20 years of age (kg) ^a

<46.0

1.00

1.00

46.0–49.9

1.87 (0.63–5.54) 0.26

0.56 (0.17–1.92) 0.36

50.0–54.9

0.89 (0.30–2.69) 0.84

0.74 (0.22–2.50) 0.62

55.0+

1.18 (0.39–3.60) 0.78

4.43 (0.76–26.0) 0.09

(Trend P = 0.86)

(Trend P = 0.26)

Weight change since age 20 (kg) ^a

<−2

1.86 (0.67–5.16) 0.23

0.48 (0.09–2.61) 0.40

±2

1.00

1.00

2+

1.98 (0.89–4.41) 0.09

1.05 (0.34–3.27) 0.93

(Trend P = 0.54)

(Trend P = 0.38)

Weight at diagnosis (kg) ^b

<48.5

1.00

1.00

48.5–53.4

0.79 (0.29–2.16) 0.64

1.80 (0.56–5.86) 0.33

53.5–60.4

0.98 (0.38–2.58) 0.97

1.07 (0.32–3.64) 0.91

60.4+

1.55 (0.59–4.06) 0.37

3.71 (0.93–14.7) 0.06

(Trend P = 0.33)

(Trend P = 0.15)

Duration from symptom onset (years)^a

<1.0

1.00

1.00

1.0–1.9

1.30 (0.47–3.62) 0.62

2.21 (0.61–8.09) 0.23

2.0–5.9

2.22 (0.85–5.79) 0.10

3.95 (1.16–13.5) 0.03

6.0+

1.64 (0.57–4.76) 0.36

14.3 (3.08–66.5) <0.01

(Trend P = 0.20)

(Trend P < 0.01)