Table 2 The genotype and allele frequencies of rs1137101 polymorphism of LEPR gene in knee OA patients and healthy controls
Groups | Number | Genotype frequencies (%) | Allele frequencies (%) | χ2 | P-value | |||
|---|---|---|---|---|---|---|---|---|
GG | AG/GA | AA | G | A | ||||
Cases | 587 | 267 (45.49) | 271 (46.17) | 49 (8.35) | 805 (68.57) | 369 (31.43) | 2.96 | 0.85 |
Control | 628 | 258 (41.08) | 291 (46.34) | 79 (12.58) | 807 (64.25) | 449 (35.75) | 0.05 | 0.83 |
Total | 1215 | 523 (43.05) | 571 (47.00) | 121 (9.96) | 1617 (66.54) | 813 (33.46) | 1.55 | 0.21 |
χ2 = 6.52, P = 0.038          2 = 5.06, P = 0.024 | ||||||||