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Table 5 Comparison of anthropometric, clinical and densitometric variables between patients with AS with and without cachexia according to the IGWS definition

From: Is there a relation between pre-sarcopenia, sarcopenia, cachexia and osteoporosis in patients with ankylosing spondylitis?

  AS patients with cachexia N = 8 AS patients without cachexia N = 59 P
Age (yrs): m (SD) 36.5 (13.6) 41.5 (10.7) NS
Height (m): m (SD) 1.73 (0.06) 1.72 (0.06) NS
Weight (kg): m (SD) 53.7 (11.0) 75.2 (11.9) <0.0001
BMI (kg/m2): m (SD) 21.6 (3.6) 26.7 (3.7) <0.0001
Disease duration (yrs): m (SD) 8.3 (9.1) 9.4 (6.6) NS
LS BMD (g/cm2): m (SD) 1.150 (0.23) 0.892 (0.14) <0.0001
LS T-score: m (SD) −2.45 (3.4) −0.38 (1.2) <0.0001
TH BMD(g/cm2): m (SD) 0.856 (0.13) 0.991 (0.23) 0.037
TH T-score: m (SD) −1.45 (1.4) −0.44 (1.1) 0.016
Osteoporosis: n (%) 6 (75.0) 7 (11.9) <0.0001
BASDAI (0–10): m (SD) 5.4 (2.4) 3.5 (2.5) 0.007
BASMI (0–10): m (SD) 3.5 (2.2) 2.7 (2.7) NS
BASFI (0–100): m (SD) 52.3 (26.5) 35.0 (25.5) NS
BAS-G (0–100): m (SD) 29.5 (16.8) 15.9 (22.6) NS
Hand grip strength (kg): m (SD) 19.1 (7.0) 23.8 (9.8) NS
Get-up and go test (sec) < 10 sec: n (%) 6 (75.0) 41 (74.5) NS
Arm circumference (cm): m (SD) 25.8 (1.9) 29.5 (3.9) <0.0001
Waist circumference (cm): m (SD) 78.4 (10.8) 92.8 (11.4) <0.0001
MNA test (0–17): m (SD) 0.62 (0.4) 0.19 (0.3) 0.008
SASSS (0–72): m (SD) 8.3 (4.7) 10.6 (16.6) NS
CRP (mg/l): m (SD) 39.2 (10.1) 11.6 (10.1) 0.013
ESR (mm/H): m (SD) 44.1 (22.3) 24.3 (18.4) 0.031
Patients taking TNFi: n (%) 21 (35.6) 1 (12.5) NS
  1. BMI body mass index, BMD bone mineral density, CRP C-reactive protein, ESR erythrocyte sedimentation rate, LS lumbar spine, MNA Mini Nutritional Assessment, SASSS Stoke Ankylosing Spondylitis Spinal Score, TH total hip