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Table 5 Comparison of anthropometric, clinical and densitometric variables between patients with AS with and without cachexia according to the IGWS definition

From: Is there a relation between pre-sarcopenia, sarcopenia, cachexia and osteoporosis in patients with ankylosing spondylitis?

 

AS patients with cachexia N = 8

AS patients without cachexia N = 59

P

Age (yrs): m (SD)

36.5 (13.6)

41.5 (10.7)

NS

Height (m): m (SD)

1.73 (0.06)

1.72 (0.06)

NS

Weight (kg): m (SD)

53.7 (11.0)

75.2 (11.9)

<0.0001

BMI (kg/m2): m (SD)

21.6 (3.6)

26.7 (3.7)

<0.0001

Disease duration (yrs): m (SD)

8.3 (9.1)

9.4 (6.6)

NS

LS BMD (g/cm2): m (SD)

1.150 (0.23)

0.892 (0.14)

<0.0001

LS T-score: m (SD)

−2.45 (3.4)

−0.38 (1.2)

<0.0001

TH BMD(g/cm2): m (SD)

0.856 (0.13)

0.991 (0.23)

0.037

TH T-score: m (SD)

−1.45 (1.4)

−0.44 (1.1)

0.016

Osteoporosis: n (%)

6 (75.0)

7 (11.9)

<0.0001

BASDAI (0–10): m (SD)

5.4 (2.4)

3.5 (2.5)

0.007

BASMI (0–10): m (SD)

3.5 (2.2)

2.7 (2.7)

NS

BASFI (0–100): m (SD)

52.3 (26.5)

35.0 (25.5)

NS

BAS-G (0–100): m (SD)

29.5 (16.8)

15.9 (22.6)

NS

Hand grip strength (kg): m (SD)

19.1 (7.0)

23.8 (9.8)

NS

Get-up and go test (sec) < 10 sec: n (%)

6 (75.0)

41 (74.5)

NS

Arm circumference (cm): m (SD)

25.8 (1.9)

29.5 (3.9)

<0.0001

Waist circumference (cm): m (SD)

78.4 (10.8)

92.8 (11.4)

<0.0001

MNA test (0–17): m (SD)

0.62 (0.4)

0.19 (0.3)

0.008

SASSS (0–72): m (SD)

8.3 (4.7)

10.6 (16.6)

NS

CRP (mg/l): m (SD)

39.2 (10.1)

11.6 (10.1)

0.013

ESR (mm/H): m (SD)

44.1 (22.3)

24.3 (18.4)

0.031

Patients taking TNFi: n (%)

21 (35.6)

1 (12.5)

NS

  1. BMI body mass index, BMD bone mineral density, CRP C-reactive protein, ESR erythrocyte sedimentation rate, LS lumbar spine, MNA Mini Nutritional Assessment, SASSS Stoke Ankylosing Spondylitis Spinal Score, TH total hip