Skip to main content

Table 3 Sensitivity, specificity, positive predictive value and negative predictive value of HR-pQCT

From: Visual detection of cortical breaks in hand joints: reliability and validity of high-resolution peripheral quantitative CT compared to microCT

Joints Total number of breaks on HR-pQCT Total number of breaks on μCT Sensitivity Specificity Positive predictive value Negative predictive value
MCP reader 1 68 79 82.1 % 65 % 86.8 % 56.5 %
MCP reader 2 83 156 65.6 % 62.5 % 87.5 % 31.3 %
PIP reader 1 61 70 81 % 63.3 % 75.6 % 70.4 %
PIP reader 2 68 85 75.6 % 77.4 % 81.6 % 70.6 %
All reader 1 129 149 81.6 % 64 % 81.6 % 64 %
All reader 2 151 241 68.9 % 69.4 % 82.6 % 51.5 %
  1. Sensitivity, specificity, positive predictive value and negative predictive value of HR-pQCT in the detection of cortical breaks with μCT as gold standard based on the mean score of Reader 1 (readings 1 and 2), and the score of Reader 2
  2. Abbreviations: HR-pQCT high resolution peripheral quantitative computed tomography, μCT microCT