Table 1 Treatment sequences
Treatment sequence | Subjects, n | Treatment period | ||
|---|---|---|---|---|
1 | 2 | 3 | ||
A | 5 | Placebo | 2.5 mg | 10 mg |
B | 5 | 2.5 mg | 5 mg | 20 mg |
C | 5 | 5 mg | 10 mg | 40 mg |
D | 5 | 10 mg | 20 mg | 60 mg |
E | 5 | 20 mg | 40 mg | Placebo |
F | 5 | 40 mg | 60 mg | 2.5 mg |
G | 5 | 60 mg | Placebo | 5 mg |
Total | 35a | |||