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Table 3 BALP, CTX and sclerostin concentrations in the RG, WG, and CG at baseline and post-intervention

From: Direct effects of physical training on markers of bone metabolism and serum sclerostin concentrations in older adults with low bone mass

Variables

RG (n = 50)

WG (n = 50)

CG (n = 50)

BALP

 

 Baseline [%]a

41.7 ± 12.8

41.8 ± 7.6

42.2 ± 10.4

 Post-intervention [%]a

41.8 ± 12.0

42.1 ± 8.4

42.1 ± 10.2

 Change [%]b

+0.1 ± 5.0

+0.9 ± 2.6

−0.14 ± 0.57

 P value

0.33

0.05

0.19

 ANOVA

P = 0.21

 Post hoc tests

P RG − CG = 0.90; P RG − WG = 0.47; P WG − CG = 0.23

CTX

 

 Baseline [pg/mL]

303.6 ± 156.8

247.3 ± 106.2

259.1 ± 110.2

 Post-intervention [pg/mL]

276.4 ± 143.6

253.9 ± 107.5

256.7 ± 111.2

 Change [pg/mL]b

−27.2 ± 33.5

+6.6 ± 30.7

−2.4 ± 14.6

 P value (paired t)

<0.01

0.11

0.37

 ANOVA

P < 0.01

 Post hoc tests

P RG − CG < 0.01; P RG − WG < 0.01; P WG − CG = 0.20

SCLEROSTIN

 

 Baseline [pmol/L]

26.8 ± 14.0

23.6 ± 10.0

24.0 ± 8.8

 Post-intervention [pmol/L]

29.8 ± 15.7

29.9 ± 10.8

24.2 ± 8.8

 Change [pmol/L]b

+2.9 ± 8.6

+6.3 ± 12.1

−0.2 ± 8.7

 P value

0.08

<0.01

0.49

 ANOVA

P < 0.01

 Post hoc tests

P TG − CG = 0.1; P TG − WG = 0.11; P WG − CG < 0.01

  1. Abbreviations: BALP bone specific alkaline phosphatase, CTX C-terminal telopeptide of type-I collagen, RG resistance exercise group, WG walking group, CG control group
  2. aBALP expressed as a proportion of the total value of serum ALP
  3. bDifference between baseline and post-intervention data