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Table 3 Baseline fracture risk factors between patients for ‘major osteoporotic fracture’

From: Rationale of the Spanish FRAX model in decision-making for predicting osteoporotic fractures: an update of FRIDEX cohort of Spanish women

 

With Fracture (n = 108)

Without Fracture (n = 1200)

p- value

95 % CI

RR

RR 95 % CI

Age (SD)

61.6 (9.4)

56.8 (8.0)

<0.001

[2.9–6.6]

  

Age > 65 years (%)

39.8

17.4

<0.001

[12.9–31.9]

2.77 a

[1.9–4.0]

BMI (SD)

27.6 (4.6)

28.0 (4.7)

0.518

ns

-

-

BMI < 20 (%)

5.6

2.3

0.036

[1.1–7.7]

2.27 b

[1.1–4.4]

Previous fracture (%)

42.6

19.5

<0.001

[13.5–32.7]

2.72

[1.9–3.9]

Parental hip fracture (%)

15.7

14.1

0.637

ns

1.13

[0.7–1.8]

Smoker (%)

9.3

11.7

0.452

ns

0.79

[0.4–1.4]

Alcohol risk (%)

0.9

0.7

0.541

ns

1.35

[0.2–5.4]

Corticoids (%)

8.3

4.7

0.093

ns

1.74

[0.9–3.2]

Rheumatoid arthritis (%)

2.8

1.0

0.120

ns

2.46

[0.9–5.7]

Falls previous year (%)

34.3

22.3

0.005

[2.7–21.3]

1.71

[1.2–2.5]

Osteoporosis (baseline DXA) (%)

51.9

26.1

<0.001

[16.1–33.6]

6.07 c

[2.9–12.9]

Osteopenia (baseline DXA) (%)

41.7

49.9

0.103

ns

2.95 d

[1.4–6.4]

Normal (baseline DXA) (%)

6.5

24.0

<0.001

[12.3–22.7]

-

-

  1. CI confidence interval, RR relative risk, SD standard deviation, BMI body mass index, ns non statistical significance, DXA dual-energy X-ray absorptiometry
  2. a < 65 vs ≥ 65 years
  3. b < 20 vs ≥ 20
  4. c Osteoporosis vs normal
  5. d Osteopenia vs normal