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Table 2 Economic evaluation of obesity interventions in OA populations

From: Addressing obesity in the management of knee and hip osteoarthritis – weighing in from an economic perspective

Author, Year, Country Intervention Target population Type of economic evaluation, time horizon Costing perspective, costs included, base year for costing Outcome measurement Costs Cost- efficacy
Sevick MA, et al, 2009 [38] 18 month dietary and exercise intervention in overweight/obese elderly patients with knee OA The ADAPT trial - 4 arms in the trial: healthy lifestyle control, diet, exercise, exercise and diet. participants aged ≥ 60 year, BMI ≥ 28 kg/M2,with radiographic evidence of knee OA (but not advanced stage radiographic evidence) Cost-efficacy study over 18 months; no modelled analysis. Managed care organisation payer perspective. Intervention costs (staff time, facilities, equipment and materials) collected prospectively and self- reported health services consumed by participants over the duration of the trial. All costs adjusted to Yr. 2000 USD WOMAC (function, pain, stiffness components separately), weight change, 6 MWT and stair climb. Total intervention costs and health service utilisation costs in USD per participant per month: control: $32, Diet only: $160, Exercise only: $152, Exercise and Diet:$304 Exercise and diet intervention most cost effective for improved self-reported function, pain and stiffness (USD 24 per PPI in function, USD 20 per PPI in pain, USD 56 per PPI in stiffness) compared to healthy control. Diet arm was most cost effective for reducing weight (USD 35 per PPR in baseline body weight)
  1. ADAPT arthritis, diet and physical activity promotion diet, BMI body mass index, WOMAC Western Ontario and McMaster Universities Arthritis Index, 6 MWT 6 min walk test, USD US dollars, PPI percentage point improvement, PPR percentage point reduction, OA osteoarthritis, PPI percentage point increase