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Table 4 Logistic regression analysis of association between GI events and treatment initiation

From: Association between gastrointestinal events and osteoporosis treatment initiation in women diagnosed with osteoporosis in France: a retrospective analysis

Effect Initiated any treatment vs. no treatment initiated
Post-index GI event (ref: no post-index GI event) Odds ratio 95 % CI p value
 Among patients without pre-index GI problems 0.293 (0.25, 0.34) <0.0001
 Among patients with pre-index GI problems 0.257 (0.20, 0.31) <0.0001
Age group    
 65–74 vs. 55–64 1.319 (1.14, 1.47) 0.0024
 75–84 vs. 55–64 1.538 (1.26, 1.72) <0.0001
 85+ vs. 55–64 1.271 (1.05, 1.63) 0.1432
Pre-index medication use    
 Gastro-protective agents 1.755 (1.58, 1.95) <0.0001
 NSAIDs 1.337 (1.23, 1.45) <0.0001
 Glucocorticoids 1.254 (1.13, 1.39) <0.0001
Charlson comorbidity index score 0.929 (0.89, 0.97) 0.0093
  1. GI gastrointestinal, NSAIDs non-steroidal anti-inflammatory drugs
  2. CI confidence interval