Table 2 The results of meta-analysis and subgroup analysis
From: The efficacy of topical tranexamic acid in total hip arthroplasty: a meta-analysis
Outcomes | No. studies | No. Patients | SMD or OR (95Â % CI) | P value | Heterogeneity | |
|---|---|---|---|---|---|---|
IA TXA | IV TXA | |||||
Total blood loss | 10 | 642 | 635 | −297.65 (−371.60 to −223.69) | <0.01 | I2 = 71 % |
 RCT | 5 | 281 | 247 | −378.96 (−454.12 to −303.81) | <0.01 | I2 = 18 % |
 nRCT | 5 | 102 | 101 | −218.88 (−271.68 to −166.08) | <0.01 | I2 = 30 % |
Total drain out | 6 | 363 | 428 | −164.68 (−236.63 to −92.73) | <0.01 | I2 = 96 % |
 RCT | 4 | 179 | 164 | −187.97 (−276.77 to −99.18) | <0.01 | I2 = 93 % |
 nRCT | 2 | 184 | 284 | −121.95 (−318.92 to 75.03) | 0.22 | I2 = 99 % |
Transfusion rates | 12 | 871 | 1893 | 0.29 (0.19 to 0.44) | <0.01 | I2 = 46 % |
 RCT | 5 | 319 | 304 | 0.21 (0.13 to 0.34) | <0.01 | I2 = 0 % |
 nRCT | 7 | 552 | 1589 | 0.36 (0.19 to 0.66) | <0.01 | I2 = 59 % |
 Hb drop | 11 | 774 | 822 | −0.66 (−0.91 to −0.41) | <0.01 | I2 = 81 % |
 RCT | 5 | 292 | 280 | −0.72 (−1.24 to −0.19) | <0.01 | I2 = 88 % |
 nRCT | 6 | 482 | 542 | −0.61 (−0.87 to −0.36) | <0.01 | I2 = 71 % |
Length of hospital stay | 6 | 542 | 602 | −0.40 (−0.91 to 0.11) | 0.13 | I2 = 83 % |
 RCT | 2 | 181 | 180 | −0.27 (−1.29 to 0.75) | 0.60 | I2 = 66 % |
 nRCT | 4 | 361 | 422 | −0.51 (−1.37 to 0.35) | 0.24 | I2 = 88 % |
 DVTs | 6 | 348 | 1355 | 1.19 (0.40 to 3.57) | 0.75 | I2 = 0 % |
 RCT | 3 | 162 | 160 | 1.28 (0.31 to 5.29) | 0.73 | I2 = 0 % |
 nRCT | 3 | 186 | 1195 | 1.07 (0.19 to 6.12) | 0.94 | I2 = 0 % |
 PE | 2 | 224 | 1281 | 1.11 (0.11 to 10.81) | 0.93 | I2 = 6 % |
 nRCT | 2 | 224 | 1281 | 1.11 (0.11 to 10.81) | 0.93 | I2 = 6 % |