Table 3 Surgical and postoperative information, efficacy and safety in patients receiving preoperative and postoperative initiation of anticoagulation therapy
Characteristics | Preoperative Anticoagulation group | Postoperative anticoagulation group | Total | P value |
|---|---|---|---|---|
(n=133) | (n=89) | (n=222) | ||
Surgical information | ||||
General anaesthesia, n (%) | 37 (27.82) | 17 (19.10) | 54 (34.32) | |
Surgery time (min),mean ± SD | 173±43 | 180±53 | 176±34 | 0.287 |
Intraoperative bleeding (mL),mean ± SD | 208±183 | 228±179 | 216±135 | 0.204 |
Intraoperative blood transfusion, n (%) | 9 (6.77) | 6 (6.74) | 15 (6.76) | |
Postoperative information | ||||
Postoperative blood transfusion, n (%) | 22 (16.54) | 13 (14.61) | 35 (15.77) | |
Postoperative drainage (mL),mean ± SD | 212±154 | 244±196 | 225±133 | 0.403 |
Reduction in hemoglobin concentrations (g/L) | 23±11 | 27±13 | 25±14 | 0.143 |
Hospital stays(days),mean ± SD | 20±5 | 19±6 | 20±4 | 0.104 |
Efficacy assessment, n (%) | ||||
Symptomatic DVT | 1 (0.75) | 1 (1.1) | 2 (0.90) | |
Symptomatic PE | 2 (1.5) | 1 (1.1) | 3 (1.35) | |
Safety assessment, n (%) | ||||
Major bleeding | 0 (0) | 0 (0) | 0 (0) | |
Minor bleeding | 5 (3.76) | 3 (3.37) | 8 (3.60) | |
Thrombocytopenia | 0 (0) | 1 (1.1) | 1 (0.45) | |
Elevated aminotransferase | 0 (0) | 1 (1.1) | 1 (0.45) | |
Suspicious allergic reaction | 1 (0.75) | 0 (0) | 1 (0.45) |