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Table 4 Multivariate association in osteogenic differentiation (*p < 0.05)

From: Anterior cruciate ligament remnant tissue harvested within 3-months after injury predicts higher healing potential

 

ALP activity

Osteocalcin mRNA

ALP mRNA

Runx2 mRNA

 

p

OR

95 % CI

p

OR

95 % CI

p

OR

95 % CI

p

OR

95 % CI

Interval from injury to surgeryb, < 90 days

0.263

2.416

0.515–11.337

0.009*

20.579

2.119–199.882

0.022*

6.527

1.308–32.557

0.047*

5.247

1.023–26.922

10 ≤ age <20 year-oldc

0.895

0.884

0.142–5.491

0.384

2.683

0.290–24.782

0.962

0.954

0.141–6.481

0.592

0.600

0.092–3.895

20 ≤ age <30 year-oldc

0.240

0.277

0.033–2.356

0.909

1.155

0.097–13.787

0.742

1.420

0.176–11.451

0.480

0.463

0.055–3.924

Sexa Female

0.030*

12.831

1.279–128.746

0.850

0.831

0.123–5.606

0.885

1.131

0.212–6.041

0.550

0.601

0.113–3.191

Meniscal injuryd

0.218

2.400

0.596–9.670

0.198

2.600

0.606–11.152

0.360

1.920

0.475–7.766

0.803

1.200

0.287–5.021

Chondral injuryd

0.000

0.000

0.000–0.000

1.000

1.000

0.081–12.270

0.000

0.000

0.000–0.000

0.913

1.150

0.093–14.188

Combined meniscal or chondral injuriesd

0.402

1.800

0.455–7.127

0.346

2.000

0.473–8.462

0.588

1.467

0.367–5.858

0.519

1.615

0.376–6.940

  1. aUse “male” category as reference
  2. bUse “interval more than 90 days” category as reference
  3. cUse “age more than 30-year old” category as reference
  4. dUse “no meniscal or chondral injuries” category as reference