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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: Influence of dendritic polyglycerol sulfates on knee osteoarthritis: an experimental study in the rat osteoarthritis model

Fig. 3

a-c Comparison of untreated rats and rats treated with dPGS concerning detectable dPGS deposition in the liver, spleen and kidney and development of body weight in adult male Wistar rats over the course of 11 weeks. a-b: Paraffin sections of organs derived from male adult Wistar rats were stained using AB. Depicted are the remaining dPGS nanoparticular compounds in the liver, spleen and kidney of the treated rats (b1-3) in contrast to untreated rats (a1-3). Scale bars: 200 μm (a1-2, b1-2) and 100 μm (a3, b3). (a1) black arrow: mast cell, (a2) white arrow: Kupffer cell, (b2) red arrow: spleen macrophage. c: Depicted are the control animals and the animals treated with dPGS (n = 12). The weight is depicted as the percentage of weight in comparison to the weight at the beginning

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