Table 2 Differentially expressed genes in PC-treated and PC-E-treated cells compared with untreated cells
Biological process | Gene name | Gene ID | Differ Expre (fold)* PC | Differ Expre (fold)** PC-E | Description |
|---|---|---|---|---|---|
Muscle tissue development | |||||
IGFBP5 | AW157548 | 8.57 | 1.55 | Insulin-like growth factor binding protein 5 | |
CACNB4 | NM_000726 | 2.73 | 0.00 | Calcium channel, voltage-dependent, beta 4 subunit | |
TPM1 | AI521618 | 2.43 | 0.00 | Tropomyosin 1 (alpha) | |
JAG1 | U61276 | 2.02 | 0.00 | Jagged 1 (Alagille syndrome) | |
MORF4L2 | H43976 | 1.90 | 0.00 | Mortality factor 4 like 2 | |
NRG1 | NM_013957 | 1.88 | 0.00 | Neuregulin 1 | |
SIRT2 | BG722779 | 1.86 | 0.00 | Sirtuin (silent mating type information regulation 2 homolog) 2 | |
NF1 | D12625 | 1.80 | 0.00 | Neurofibromin 1 | |
OBSL1 | BF446688 | 1.78 | 0.00 | Obscurin-like 1 | |
MBNL1 | AA732240 | 1.73 | 0.00 | Muscleblind-like (Drosophila) | |
TPM1 | NM_000366 | 1.72 | 0.00 | Tropomyosin 1 (alpha) | |
CAV2 | AA150110 | 1.67 | 0.00 | Caveolin 2 | |
RXRA | BE675800 | 1.66 | 0.00 | Retinoid X receptor, alpha | |
NR2F2 | AL554245 | 1.63 | 0.00 | Nuclear receptor subfamily 2, group F, member 2 | |
TCF7L2 | AV721430 | 1.61 | 2.00 | Transcription factor 7-like 2 (T-cell specific, HMG-box) | |
TBX2 | U28049 | −4.17 | 0.00 | T-box 2 | |
ADRB2 | NM_000024 | −2.36 | 0.00 | Adrenergic, beta-2-, receptor, surface | |
SORT1 | BE742268 | −1.93 | 0.00 | Sortilin 1 | |
GJC1 | NM_005497 | −1.77 | −3.09 | Gap junction protein, gamma 1, 45 kDa | |
CENPF | U30872 | −1.77 | 0.00 | Centromere protein F, 350/400 ka (mitosin) | |
BCL2 | NM_000657 | −1.71 | 1.55 | B-cell CLL/lymphoma 2 | |
TBX3 | U69556 | −1.71 | 1.77 | T-box 3 | |
SDC1 | NM_002997 | −1.65 | −1.89 | Syndecan 1 | |
TBX5 | AW269421 | −1.54 | 0.00 | T-box 5 | |
RARB | NM_015854 | −1.51 | 0.00 | Retinoic acid receptor, beta | |
Skeletal development | |||||
ANXA2 | D28364 | 2.17 | 0.00 | Annexin A2 | |
VDR | AA772285 | 2.11 | 0.00 | Vitamin D (1,25- dihydroxyvitamin D3) receptor | |
GNAS | AI693143 | 1.95 | 1.60 | GNAS complex locus | |
ACAN | NM_001135 | 1.80 | −1.51 | Aggrecan | |
COL1A1 | AI743621 | 1.66 | 0.00 | Collagen, type I, alpha 1 | |
COL1A2 | AA628535 | 1.88 | 0.00 | Collagen, type I, alpha 2 | |
COL11A1 | NM_001854 | 1.50 | 0.00 | Collagen, type XI, alpha 1 | |
COL12A1 | AU146651 | 1.93 | 1.51 | Collagen, type XII, alpha 1 | |
MSX2 | D89377 | 1.85 | 0.00 | Msh homeobox 2 | |
GHR | NM_000163 | 1.76 | 0.00 | Growth hormone receptor | |
MEF2C | AL536517 | 1.59 | 0.00 | Myocyte enhancer factor 2C | |
THRA | NM_003250 | 1.57 | 1.60 | Thyroid hormone receptor, alpha | |
RUNX2 | AW469546 | 1.55 | 1.89 | Runt-related transcription factor 2 | |
CLEC3B | NM_003278 | 1.55 | 3.26 | Exosome component 7 | |
MEF2C | N22468 | 1.55 | 0.00 | Myocyte enhancer factor 2C | |
IGFBP4 | NM_001552 | 1.54 | 0.00 | Insulin-like growth factor binding protein 4 | |
PRKRA | AA279462 | 1.53 | 0.00 | Protein kinase, interferon-inducible RNA dependent activator | |
TNFRSF11B | NM_002546 | 1.50 | −2.76 | Tumor necrosis factor receptor superfamily, member 11b | |
BMPR1B | AA935461 | −2.12 | 0.00 | Bone morphogenetic protein receptor, type IB | |
ANKH | AF274753 | −1.93 | −1.71 | Ankylosis, progressive homolog (mouse) | |
ACVR2A | NM_001616 | −1.89 | 0.00 | Activin A receptor, type IIA | |
CYTL1 | NM_018659 | −1.83 | 0.00 | Cytokine-like 1 | |
TBX3 | U69556 | −1.71 | 1.77 | T-box 3 (ulnar mammary syndrome) | |
SOX9 | NM_000346 | −1.71 | 0.00 | SRY (sex determining region Y)-box 9 | |
FOXC2 | NM_005251 | −1.68 | 0.00 | Forkhead box C2 (MFH-1, mesenchyme forkhead 1) | |
KIAA1217 | BC017424 | −1.66 | 0.00 | KIAA1217 | |
MMP9 | NM_004994 | −1.61 | 0.00 | Matrix metallopeptidase 9 | |
TGFBR2 | NM_003242 | −1.51 | −1.97 | Transforming growth factor, beta receptor II (70/80 kDa) |