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Table 1 Overview of the criteria and cutoffs used in historical algorithms to diagnose gout

From: Validity of gout diagnosis in Swedish primary and secondary care - a validation study

Criteria

Rome 1963

New York 1966

ARA 1977

Mexico 2010

Netherlands 2010

Cutoff for gout classification

≥2 of 4 criteria

≥2 of 4 criteria

6 of 12 criteria OR presence of MSU in SF

4 of 8 criteria OR presence of MSU in SF

>8 pointsa

Serum uric acid, μmol/L,

Male >420 female >360

 

>2 SD normal

>2 SD normal

>350 (3.5 points)

Presence of tophi

X

X

X

X

X (13 points)

MSU crystals in SF or tissue

x

 

(x)

  

History of attacks of painful joint swelling with abrupt onset and resolution within 2 weeks

≥2 attacks

≥2 attacks

   

A history or observation of podagra

 

X

 

X

 

Rapid response to colchicine treatment, defined as a major reduction in the objective signs of inflammation within 48 h

 

X

   

More than one attack of acute arthritis

  

X

X

 

Maximum inflammation developed within 1 day

  

X

X

X (0.5 point)

Oligoarthritis attack

  

X

  

Redness observed over the joints

  

X

X

X (1 point)

First MTP joint painful or swollen

  

X

  

Unilateral first MTP joint attack

  

X

  

Unilateral tarsal joint attack

  

X

X

 

Asymmetrical swelling within a joint on X-ray

  

X

  

Subcortical cysts without erosions on X-ray

  

X

  

Joint culture negative for organisms during attack

  

X

  

Mono and/or oligoarticular attacks

   

X

X (2 points)

Male sex

    

X (2 points)

MTP1 involvement

    

X (2.5 points)

Hypertension or more than one cardiovascular diseaseb

    

X (1.5 points)

  1. aA summed score of 4 or less excludes gout; 8 or more suggests gout; between 4 and 8 suggests the need for SF analysis
  2. bCardiovascular disease was defined as angina pectoris, myocardial infarction, heart failure, cerebrovascular accident, transient ischemic attack or peripheral vascular disease
  3. Abbreviations: MSU monosodium urate, MTP metatarsophalangeal, SF synovial fluid