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Table 4 Adjusted hazard ratios (HRs) and 95 % confidence intervals (CIs) for different fracture locations in the time-dependent model among age group

From: Tamoxifen use reduces the risk of osteoporotic fractures in women with breast cancer in Asia: a nationwide population-based cohort study

Age group Tamoxifen user vs. non-user HR (95 % CI) p-value Interaction p
Overall     0.29
  <50 0.54 (0.36-0.82) 0.004  
  50-59 0.58 (0.40-0.83) 0.003  
  60-69 0.66 (0.50-0.88) 0.005  
  70+ 0.59 (0.48-0.74) <0.0001  
Hip fracture     0.046
  <50 0.39 (0.19-0.81) 0.01  
  50-59 0.38 (0.20-0.72) 0.003  
  60-69 0.56 (0.38-0.81) 0.002  
  70+ 0.61 (0.47-0.78) 0.0001  
Vertebral fracture     0.86
  <50 0.59 (0.34-1.03) 0.06  
  50-59 0.74 (0.46-1.19) 0.21  
  60-69 0.84 (0.54-1.32) 0.46  
  70+ 0.54 (0.34-0.85) 0.008  
Wrist fracture     0.26
  <50 0.90 (0.31-2.57) 0.84  
  50-59 0.76 (0.25-2.34) 0.63  
  60-69 1.44 (0.20-10.6) 0.72  
  70+ 1.10 (0.07-17.9) 0.94  
  1. Manually adjusted for monthly income, comorbidity and aromatase inhibitor use before the end point