Table 4 Adjusted hazard ratios (HRs) and 95 % confidence intervals (CIs) for different fracture locations in the time-dependent model among age group
Age group | Tamoxifen user vs. non-user HR (95 % CI) | p-value | Interaction p | |
|---|---|---|---|---|
Overall | 0.29 | |||
<50 | 0.54 | (0.36-0.82) | 0.004 | |
50-59 | 0.58 | (0.40-0.83) | 0.003 | |
60-69 | 0.66 | (0.50-0.88) | 0.005 | |
70+ | 0.59 | (0.48-0.74) | <0.0001 | |
Hip fracture | 0.046 | |||
<50 | 0.39 | (0.19-0.81) | 0.01 | |
50-59 | 0.38 | (0.20-0.72) | 0.003 | |
60-69 | 0.56 | (0.38-0.81) | 0.002 | |
70+ | 0.61 | (0.47-0.78) | 0.0001 | |
Vertebral fracture | 0.86 | |||
<50 | 0.59 | (0.34-1.03) | 0.06 | |
50-59 | 0.74 | (0.46-1.19) | 0.21 | |
60-69 | 0.84 | (0.54-1.32) | 0.46 | |
70+ | 0.54 | (0.34-0.85) | 0.008 | |
Wrist fracture | 0.26 | |||
<50 | 0.90 | (0.31-2.57) | 0.84 | |
50-59 | 0.76 | (0.25-2.34) | 0.63 | |
60-69 | 1.44 | (0.20-10.6) | 0.72 | |
70+ | 1.10 | (0.07-17.9) | 0.94 | |