Table 1 Demographic data and clinical characteristics of patients with adult-onset Still’s disease (AOSD), patients with systemic lupus erythematosus (SLE), and healthy controls (HC)#
AOSD (n = 52) | SLE (n = 36) | HC (n = 16) | |
|---|---|---|---|
Age at study entry (years) | 37.1 ± 13.4 | 38.0 ± 12.1 | 32.5 ± 6.1 |
Proportion of females | 37 (71.2%) | 30 (83.3%) | 10 (62.5%) |
Serum creatinine (mg/dL) | 0.84 ± 0.14 | 0.96 ± 0.92 | 0.89 ± 0.17 |
Body mass index (kg/m2) | 22.6 ± 2.7 | 21.4 ± 1.8* | 21.8 ± 1.7 |
AOSD activity scores | 4.3 ± 2.0 | NA | NA |
CRP levels (normal <0.3 mg/dL) | 2.66 ± 2.44 | NA | NA |
Ferritin levels (normal <280 μg/L) | 1458 ± 4717 | NA | NA |
SLEDAI | NA | 10.0 ± 1.0 | NA |
C3 (normal 84–160 mg/dL) | NA | 86.9 ± 5.9 | NA |
C4 (normal 12–36 mg/dL) | NA | 19.6 ± 2.1 | NA |
Anti-dsDNA (normal <92.7U/mL) | NA | 251.4 ± 36.4 | NA |
Nephritis | 0 (0.0%) | 11 (30.6%)** | NA |
Smoker (past) | 10 (19.2%) | 7 (19.4%) | 3 (18.8%) |
Smoker (present) | 6 (11.5%) | 5 (13.9%) | 2 (12.5%) |
Hypertension | 4 (7.7%) | 9 (25.0%)*§ | 0 (0.0%) |