Skip to main content

Table 1 Demographic data and clinical characteristics of patients with adult-onset Still’s disease (AOSD), patients with systemic lupus erythematosus (SLE), and healthy controls (HC)#

From: The potential role of advanced glycation end products (AGEs) and soluble receptors for AGEs (sRAGE) in the pathogenesis of adult-onset still’s disease

  AOSD (n = 52) SLE (n = 36) HC (n = 16)
Age at study entry (years) 37.1 ± 13.4 38.0 ± 12.1 32.5 ± 6.1
Proportion of females 37 (71.2%) 30 (83.3%) 10 (62.5%)
Serum creatinine (mg/dL) 0.84 ± 0.14 0.96 ± 0.92 0.89 ± 0.17
Body mass index (kg/m2) 22.6 ± 2.7 21.4 ± 1.8* 21.8 ± 1.7
AOSD activity scores 4.3 ± 2.0 NA NA
CRP levels (normal <0.3 mg/dL) 2.66 ± 2.44 NA NA
Ferritin levels (normal <280 μg/L) 1458 ± 4717 NA NA
SLEDAI NA 10.0 ± 1.0 NA
C3 (normal 84–160 mg/dL) NA 86.9 ± 5.9 NA
C4 (normal 12–36 mg/dL) NA 19.6 ± 2.1 NA
Anti-dsDNA (normal <92.7U/mL) NA 251.4 ± 36.4 NA
Nephritis 0 (0.0%) 11 (30.6%)** NA
Smoker (past) 10 (19.2%) 7 (19.4%) 3 (18.8%)
Smoker (present) 6 (11.5%) 5 (13.9%) 2 (12.5%)
Hypertension 4 (7.7%) 9 (25.0%)*§ 0 (0.0%)
  1. Data are presented as mean ± SD or number (percentage); NA: not applicable.
  2. CRP: C-reactive protein; SLEDAI: SLE disease activity index; C3: complement 3; C4: complement 4; Anti-ds DNA: anti-double strand DNA antibody; Nephritis is defined by persistent proteinuria (>0.5 g/24 hours) or pathological examination of renal biopsy specimens showing lupus nephritis. *P < 0.05, **p < 0.001, vs. AOSD.
  3. §p < 0.001, vs. Healthy controls.