Table 9 Thromboprophylaxes
Risk factors (thromboprophylaxes) | Studies reporting on a risk factor for THA or TKA: total number, number reporting a significant (p ≤ .05) increased (+) or decreased (−) risk, and number with no significant association (p > .05) | |||||||
|---|---|---|---|---|---|---|---|---|
THA | TKA | |||||||
N | p ≤ .05 | p > .05 | N | p ≤ .05 | p > .05 | |||
+ | - | + | - | |||||
Chemoprophylaxis (vs. no-prophylaxis) | 3 | 0 | 2 | 1 | 3 | 0 | 2 | 1 |
Enoxaparin (vs. other LMWH) | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 |
Low-dose LMWH (vs. high-dose LMWH) | - | - | - | - | 1 | 0 | 0 | 1 |
Preoperative LMWH (vs. Postoperative) | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 2 |
Oligosaccharides* (vs. LMWH) | 2 | 0 | 2 | 0 | 1 | 0 | 0 | 1 |
Direct factor-Xa inhibitor (vs. LMWH) | 5 | 0 | 4 | 1 | 5 | 1 | 2 | 2 |
Direct factor-II inhibitor (vs. LMWH) | 2 | 0 | 1 | 1 | 2 | 1 | 0 | 1 |
Partial factor-VII inhibitor (vs. LMWH) | - | - | - | - | 1 | 0 | 1 | 0 |
NSAIDS (vs. LMWH) | 2 | 0 | 0 | 2 | 1 | 0 | 0 | 1 |
VKA (vs. NSAIDS) | - | - | - | - | 1 | 1 | 0 | 0 |
ACCP-recommended prophylaxis (vs. others ) | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Extended prophylaxis (vs. short)† | 1 | 0 | 1 | 0 | 2 | 0 | 2 | 0 |
Mechanical prophylaxis (vs. chemoprophylaxis) | 1 | 0 | 0 | 1 | - | - | - | - |
Below-knee stockings (vs. up-knee) | - | - | - | - | 1 | 0 | 0 | 1 |
Earlier mobilization | 2 | 0 | 2 | 0 | 3 | 0 | 3 | 0 |
Weight bearing within 48 h | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |