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Table 3 Outcome variables

From: Internet-based randomised controlled trials for the evaluation of complementary and alternative medicines: probiotics in spondyloarthropathy

   Placebo    Probiotic   Estimated Probiotic Effect*
  Baseline Final % change Baseline Final % change Change in scale (95% CI). A positive value indicates a worsening in condition.
Intention to treat (n = 69 & n = 65)        
Global wellbeing (0–10 scale) 3.2 (2.0) 2.9 (2.3) 9.4% 4.1 (2.5) 3.7 (3.0) 9.8% 0.16 (-0.61 to 0.93)
Bowel symptoms        
Diarrhoea (0 – 10 scale) 1.9 (2.7) 1.0 (1.7) 47% 1.8 (2.6) 1.4 (2.3) 22% 0.24 (-0.36 to 0.83)
Stomach pain (0–10 scale) 2.1 (2.6) 1.2 (1.6) 42% 2.0 (2.7) 1.4 (2.2) 30% 0.17 (-0.42 to 0.76)
Blood in stools (0–10 scale) 0.6 (1.8) 0.5 (1.6) 17% 0.6 (1.6) 0.4 (1.1) 33% -0.14 (-0.55 to 0.27)
Arthritis severity        
Disease activity (0–10 scale) 3.5 (1.9) 2.9 (2.2) 17% 4.1 (2.2) 3.6 (2.6) 12% 0.20 (-0.47 to 0.86)
Function (0–10 scale) 3.1 (2.4) 2.8 (2.6) 9.7% 4.2 (2.9) 4.0 (3.2) 5% -0.04 (-0.50 to 0.43)
  1. * General linear model, with probiotic effect adjusted for age, sex, disease duration and baseline levels