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Table 4 Cartilage matrix proteins and modifying enzymes upregulated in adult cartilage relative to neonatal cartilage

From: Differential gene expression associated with postnatal equine articular cartilage maturation

Gene Name Gene Symbol GenBank ID(s)† Fold Change (A/N) p-value
Cartilage intermediate layer protein CILP CX598636.1 5.96 0.0102
   CX599486.1 7.83 0.0042
Cartilage oligomeric matrix protein COMP CX592689.1 2.53 0.0036
   CX592951.1 2.25 0.0014
   CX593277.1 2.09 0.0164
   CX597915.1 2.63 0.0041
   CX600749.1 2.43 0.0035
   CX601142.1 2.29 0.0038
Fibronectin FN1 CX594011.1 4.65 0.0075
   CX596432.1 3.35 0.0192
   CX598808.1 3.86 0.0313
   CX600436.1 4.18 0.0024
   CX601190.1 4.62 0.0017
   CX602630.1 1.31 0.1717
   peFN840 6.03 0.0013
   peFN-C1 7.24 0.0018
Frizzled-related protein FRZB CX597477.1 3.53 0.0159
   CX598716.1 3.82 0.0227
   CX604177.1 2.70 0.0015
Heparan sulfate 3-O-sulfotransferase 3A1 HS3ST3A1 CX595901.1 2.61 0.0061
Matrix metalloproteinase 1 (collagenase) MMP1 peMMP1 4.61 0.0080
Nexin-1 PN-1 CX604123.1 2.27 0.0071
Procollagen C-endopeptidase enhancer 2 PCOLCE2 CX597547.1 4.63 0.0041
   CX601347.1 2.08 0.0036
   CX604313.1 1.89 0.0013
   CX605197.1 4.64 0.0322
   CX605337.1 4.31 0.0038
Serine proteinase inhibitor, clade A, member 5 SERPINA5 CX598843.1 3.27 0.0038
Sulfatase 1 SULF1 CX596711.1 2.83 0.0043
Tissue inhibitor of metallopeptidase 2 TIMP2 CX605012.1 4.48 0.0050
  1. Gene Name & Gene Symbol: gene identity of best BLAST match homologue to cDNA or plasmid; GenBank ID: Accession number of equine cDNA spotted on the microarray (†: some IDs represent plasmid designation); Fold Change (A/N): Relative Adult/Neonate fold change; p-value: one-sample t-test p-value for probe across the four biological replicates in the total sample set.