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Table 1 Subject characteristics by study outcome

From: The association between C-reactive protein and the likelihood of progression to joint replacement in people with rheumatoid arthritis: a retrospective observational study

  All subjects No joint replacement TJR p
number (%) 2,421   2,296 94.4% 125 5.2%  
% male 26.0%   26.0%   26.4%   0.917
Mean age at index (SD) 51.9 15.0 51.4 15.0 59.4 11.5 <0.000
Prior ischaemic disease (%) 10.1   10.0   10.4   0.878
Median GP visits yr prior (IQR) 10 (6–18) 10 (6–18) 10.5 (6–18) 0.781
Mean BMI before CRP (SD) 26.9 5.6 26.9 5.6 28.1 6.3 0.051
Mean SBP before CRP (SD) 137.4 16.6 137.0 16.5 145.1 16.1 <0.000
Mean TC before CRP (SD) 5.35 1.00 5.35 1.00 5.45 0.93 0.388
Ever smoked (%) 38.4   38.8   31.5   0.107
Ln mean CRP (SD) 2.51 1.01 2.49 1.00 2.95 0.98 <0.000
Number of deaths (%) 194 8.0 185 8.1 9 7.2 0.866
  1. Index – 1st rheumatoid event; TJR – major orthopaedic intervention (ERAS definition) – standard deviation; IQR – inter-quartile range;
  2. BMI – body mass index (kg/m2); SBP – systolic blood pressure (mmHg); TC – total serum cholesterol (mmol/L); Ln – natural logarithm.
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