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Table 1 Subject characteristics by study outcome

From: The association between C-reactive protein and the likelihood of progression to joint replacement in people with rheumatoid arthritis: a retrospective observational study

 

All subjects

No joint replacement

TJR

p

number (%)

2,421

 

2,296

94.4%

125

5.2%

 

% male

26.0%

 

26.0%

 

26.4%

 

0.917

Mean age at index (SD)

51.9

15.0

51.4

15.0

59.4

11.5

<0.000

Prior ischaemic disease (%)

10.1

 

10.0

 

10.4

 

0.878

Median GP visits yr prior (IQR)

10

(6–18)

10

(6–18)

10.5

(6–18)

0.781

Mean BMI before CRP (SD)

26.9

5.6

26.9

5.6

28.1

6.3

0.051

Mean SBP before CRP (SD)

137.4

16.6

137.0

16.5

145.1

16.1

<0.000

Mean TC before CRP (SD)

5.35

1.00

5.35

1.00

5.45

0.93

0.388

Ever smoked (%)

38.4

 

38.8

 

31.5

 

0.107

Ln mean CRP (SD)

2.51

1.01

2.49

1.00

2.95

0.98

<0.000

Number of deaths (%)

194

8.0

185

8.1

9

7.2

0.866

  1. Index – 1st rheumatoid event; TJR – major orthopaedic intervention (ERAS definition) – standard deviation; IQR – inter-quartile range;
  2. BMI – body mass index (kg/m2); SBP – systolic blood pressure (mmHg); TC – total serum cholesterol (mmol/L); Ln – natural logarithm.