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Table 2 Three-point bending (beam length 6 mm) of healing mice femur fractures at 14 days treated with continuous subcutaneous administration of simvastatin

From: Locally applied Simvastatin improves fracture healing in mice

Treatment n Force at Failure (F) Energy Uptake (Nmm) Area (mm2) Young's modulus (MPa)
   m sd m sd m sd m sd
Simvastatin (5 mg) 8 5.1 1.5 2.4 0.9 11.2 1.5 201.8 128.8
Simvastatin (10 mg) 8 4.1 1.4 1.7 0.7 10.9 1.7 231.3 221.2
Control 10 3.2 1.6 1.9 1.1 9.8 2.3 163.5 67.3
p*   0.04 0.6 0.3 0.9
  1. * Signifies the p value for Scheffe's post-hoc test when comparing simvastatin 5 mg with controls. ANOVA showed a significant difference between groups (p = 0.04) M signifies mean, SD signifies standard deviation.