Table 2 Three-point bending (beam length 6 mm) of healing mice femur fractures at 14 days treated with continuous subcutaneous administration of simvastatin
From: Locally applied Simvastatin improves fracture healing in mice
Treatment | n | Force at Failure (F) | Energy Uptake (Nmm) | Area (mm2) | Young's modulus (MPa) | ||||
|---|---|---|---|---|---|---|---|---|---|
m | sd | m | sd | m | sd | m | sd | ||
Simvastatin (5 mg) | 8 | 5.1 | 1.5 | 2.4 | 0.9 | 11.2 | 1.5 | 201.8 | 128.8 |
Simvastatin (10 mg) | 8 | 4.1 | 1.4 | 1.7 | 0.7 | 10.9 | 1.7 | 231.3 | 221.2 |
Control | 10 | 3.2 | 1.6 | 1.9 | 1.1 | 9.8 | 2.3 | 163.5 | 67.3 |
p* | 0.04 | 0.6 | 0.3 | 0.9 | |||||