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Table 2 Developmental genes undergoing most striking ownregulation following exposure to dexamethasone

From: Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis

Accession

Gene

SLR 30

SLR 60

SLR 120

SLR 240

BF001670

EFNB2

0.0

-0.1

-0.2

-1.3

NM_006350.2

FST

-0.2

-0.3

-0.7

-1.2

NM_005585.1

MADH6

0.2

-0.2

-0.4

-1.1

NM_001546.1

ID4

0.3

0.1

-0.6

-1.0

NM _013409.1

FST

-0.2

-0.1

-0.3

-0.9

U16797.1

EFNB2

-0.2

-0.2

-0.7

-0.9

NM_005924.1

MEOX2

0.3

-0.2

0.0

-0.9

NM_000346.1

SOX9

-0.1

0.0

-0.5

-0.8

U41813.1

HOXA9

0.0

-0.7

-0.8

-0.8

S69738.1

CCL2

0.4

0.6

0.3

-0.8

U58111.1

VEGFC

-0.1

0.1

-0.2

-0.8

NM_018951.1

HOXA10

0.1

-0.3

-0.5

-0.7

NM_002166.1

ID2

0.4

0.0

-0.4

-0.7

NM_000600.1

IL6

0.2

0.0

-0.9

-0.6

AF022375.1

VEGF

0.1

0.2

-0.4

-0.6

AI246769

HOXA9

-0.1

-0.6

-0.7

-0.6

D13889.1

ID1

0.2

0.4

0.0

-0.6

NM_002006.1

FGF2

0.1

-0.3

-0.6

-0.6

NM_018951.1

HOXA10

0.0

-0.3

-0.3

-0.6

NM_003633.1

ENC1

0.0

0.0

-0.1

-0.6

AI333651

FZD7

0.1

-0.2

-0.1

-0.6

NM_001290.1

LDB2

0.1

0.1

-0.1

-0.4

NM_002309.2

LIF

-0.1

0.2

-0.2

-0.4

NM_002506.1

NGFB

-0.1

-0.1

-0.7

-0.4

NM_005095.1

ZNF262

0.0

0.1

0.3

-0.4

NM_001356.2

DDX3

0.1

-0.1

-0.2

-0.4

NM_020249.1

ADAMTS9

-0.4

-0.3

-0.1

-0.4

AI968085

WNT5A

0.1

-0.1

0.2

-0.4

AI819238

ID2

0.0

-0.4

-0.5

-0.4

U16153.1

ID4

0.2

-0.1

-0.5

-0.4

AI967981

ZNF45

0.0

-0.1

0.0

-0.4

U54826.1

MADH1

-0.1

0.0

-0.1

-0.4

NM_002167.1

ID3

0.2

0.0

-0.1

-0.4

NM_004333.1

BRAF

-0.4

-0.4

-0.3

-0.4

NM_005574.2

LMO2

0.0

-0.1

-0.4

-0.3

R61374

HEY1

-0.4

-0.2

-0.1

-0.3

M27968.1

FGF2

0.1

-0.1

-0.5

-0.3

NM_014240.1

LIMD1

-0.3

-0.2

-0.5

-0.3

L37882.1

FZD2

0.1

-0.2

-0.6

-0.2

  1. (SLI of ≥ 5 and a SLR ≤ -0.4 and ≥ +0.4 in one or more time points compared to control (T1)