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Table 2 Developmental genes undergoing most striking ownregulation following exposure to dexamethasone

From: Gene expression analysis in human osteoblasts exposed to dexamethasone identifies altered developmental pathways as putative drivers of osteoporosis

Accession Gene SLR 30 SLR 60 SLR 120 SLR 240
BF001670 EFNB2 0.0 -0.1 -0.2 -1.3
NM_006350.2 FST -0.2 -0.3 -0.7 -1.2
NM_005585.1 MADH6 0.2 -0.2 -0.4 -1.1
NM_001546.1 ID4 0.3 0.1 -0.6 -1.0
NM _013409.1 FST -0.2 -0.1 -0.3 -0.9
U16797.1 EFNB2 -0.2 -0.2 -0.7 -0.9
NM_005924.1 MEOX2 0.3 -0.2 0.0 -0.9
NM_000346.1 SOX9 -0.1 0.0 -0.5 -0.8
U41813.1 HOXA9 0.0 -0.7 -0.8 -0.8
S69738.1 CCL2 0.4 0.6 0.3 -0.8
U58111.1 VEGFC -0.1 0.1 -0.2 -0.8
NM_018951.1 HOXA10 0.1 -0.3 -0.5 -0.7
NM_002166.1 ID2 0.4 0.0 -0.4 -0.7
NM_000600.1 IL6 0.2 0.0 -0.9 -0.6
AF022375.1 VEGF 0.1 0.2 -0.4 -0.6
AI246769 HOXA9 -0.1 -0.6 -0.7 -0.6
D13889.1 ID1 0.2 0.4 0.0 -0.6
NM_002006.1 FGF2 0.1 -0.3 -0.6 -0.6
NM_018951.1 HOXA10 0.0 -0.3 -0.3 -0.6
NM_003633.1 ENC1 0.0 0.0 -0.1 -0.6
AI333651 FZD7 0.1 -0.2 -0.1 -0.6
NM_001290.1 LDB2 0.1 0.1 -0.1 -0.4
NM_002309.2 LIF -0.1 0.2 -0.2 -0.4
NM_002506.1 NGFB -0.1 -0.1 -0.7 -0.4
NM_005095.1 ZNF262 0.0 0.1 0.3 -0.4
NM_001356.2 DDX3 0.1 -0.1 -0.2 -0.4
NM_020249.1 ADAMTS9 -0.4 -0.3 -0.1 -0.4
AI968085 WNT5A 0.1 -0.1 0.2 -0.4
AI819238 ID2 0.0 -0.4 -0.5 -0.4
U16153.1 ID4 0.2 -0.1 -0.5 -0.4
AI967981 ZNF45 0.0 -0.1 0.0 -0.4
U54826.1 MADH1 -0.1 0.0 -0.1 -0.4
NM_002167.1 ID3 0.2 0.0 -0.1 -0.4
NM_004333.1 BRAF -0.4 -0.4 -0.3 -0.4
NM_005574.2 LMO2 0.0 -0.1 -0.4 -0.3
R61374 HEY1 -0.4 -0.2 -0.1 -0.3
M27968.1 FGF2 0.1 -0.1 -0.5 -0.3
NM_014240.1 LIMD1 -0.3 -0.2 -0.5 -0.3
L37882.1 FZD2 0.1 -0.2 -0.6 -0.2
  1. (SLI of ≥ 5 and a SLR ≤ -0.4 and ≥ +0.4 in one or more time points compared to control (T1)
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