Skip to main content

Table 2 Number of events on which overall conclusions about the efficacy of gastrointestinal protection strategies were based in a systematic review [24]

From: Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice

  Number of events recorded
Outcome Coxib NSAID + PPI NSAID + H2A
Serious gastrointestinal complications 226 3 1
Symptomatic ulcers 452 18 1
Endoscopic ulcer 522 281 250
Anaemia 464 none 1
Withdrawal due to gastrointestinal symptoms 2171 48 57
  1. Data from Hooper et al, 2004 [24]. The numbers show the actual numbers of events reported for each outcome in the paper, and the bold numbers indicate those where event rates were significantly lower with the strategy used than with NSAID alone