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Table 3 Summary of immunology studies on photooxidized osteochondral xenografts

From: Immunogenicity of unprocessed and photooxidized bovine and human osteochondral grafts in collagen-sensitive mice

  Unprocessed Photooxidized
Macrophages, cells of the innate immune system (ref. 34) ++++++ +
Adaptive T cell response to bovine grafts (cellular) + -
Adaptive T cell response to human grafts (cellular) - -
Adaptive B cell response to bovine grafts (humoral) – IgG1, IgG2a, IgG - -
Adaptive B cell response to human grafts (humoral) – IgG1, IgG2a, IgG - +
Adaptive B cell response to bovine and human grafts (humoral) – IgM ++ ++