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Table 1 Baseline demographic and clinical characteristics of treatment groups

From: Treatment of osteoarthritis of the knee with a topical diclofenac solution: a randomised controlled, 6-week trial [ISRCTN53366886]

 

Topical diclofenac (n = 107)

Vehicle control (n = 109)

Age (years)

65.0 (11.0)

64.6 (10.9)

Women, number (%)

56 (52.3)

66 (60.6)

Race/ethnicity, number (%)

  

   White

88 (82.2)

91 (83.5)

   Black

8 (7.5)

3 (2.8)

   Oriental

3 (2.8)

2 (1.8)

   Other

8 (7.5)

13 (11.9)

Weight (kg)

89.9 (18.1)

86.5 (17.3)

Height (m)

1.65 (0.11)

1.65 (0.10)

Heart rate (bpm)

74.1 (10.0)

74.3 (9.1)

Systolic blood pressure (mm Hg)

137.6 (16.3)

133.6 (15.6)

Diastolic blood pressure (mm Hg)

81.4 (9.1)

79.7 (8.7)

Total x-ray score*

7.7 (5.4)

7.0 (5.0)

Screening pain score

8.2 (2.7)

8.3 (3.0)

Baseline† pain score

13.0 (3.2)

12.8 (3.1)

Baseline† physical function score

40.7 (11.9)

40.4 (11.2)

Baseline† stiffness score

5.2 (1.5)

5.2 (1.5)

Patient global assessment score‡

3.1 (0.8)

3.2 (0.8)

Participants treating two knees at baseline, number (%)

64 (59.8)

70 (64.2)

Participants treating two knees at final, number (%)

84 (78.5)

89 (81.7)

  1. Data are presented as mean (SD) unless otherwise indicated.
  2. *Total score of joint space narrowing, marginal osteophytes formation and subchondrial sclerosis for each knee compartment (medial, lateral, patello-femoral); maximum score possible was 27.
  3. †After washout of prior therapy; pain scale ranged from 0 (no pain) to 20 (extreme pain); physical function scale ranged from 0 (no difficulty) to 68 (extreme difficulty); stiffness scale ranged from 0 (no stiffness) to 8 (extreme stiffness).
  4. ‡Patient global assessment was measured using a Likert scale, ranging from 0 (very good) to 4 (very poor).