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Table 3 Dose Escalation Regression Estimates – Inflixim ab and Etanercept Dependent Variables (Increase in dose for Inflixim ab or Etanercept 1 = yes, 0 = no)

From: Patterns of use, dosing, and economic impact of biologic agent use in patients with rheumatoid arthritis: a retrospective cohort study

Parameter

Level

Estimate

Odds-Ratio

Transformed Odds Ratio

Conditional Probability

p-value

Intercept

 

-0.3129

0.73

n.a.

n.a.

0.1702

HMO

Yes

-0.2246

0.80

1.00

0.37

0.0826

 

No

0.0000

1.00

1.25

0.42

 

Treatment

Inflixim ab

0.0000

1.00

6.38

0.42

 
 

Etanercept

-1.8529

0.16

1.00

0.10

<.0001

Region

West

0.0000

1.00

1.00

0.42

 
 

Northeast

0.6505

1.92

1.92

0.58

0.0215

 

Midwest

0.6382

1.89

1.89

0.58

0.0063

 

South

0.6252

1.87

1.87

0.58

0.0102

Pre-Period Non RA Related Costs ('000s)

Yes

0.0350

1.04

1.04

0.43

0.0185

 

No

 

1.00

1.00

0.42

 

Crohn's Disease

Yes

-0.7328

0.48

1.00

0.26

0.0477

 

No

0.0000

1.00

2.08

0.42

 

Cox-IIs

Yes

0.3064

1.36

1.36

0.50

0.0175

 

No

0.0000

1.00

1.00

0.42