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Table 3 Prescribed non-steroidal anti-inflammatory drugs and centrally acting agents. (*) means that the drug was discontinued at least 24 hrs before the study. Plasma half-life of each compound is also indicated.

From: Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study ISCRTN70707830

Fibromyalgia

Rheumatoid Arthritis

Drug

Number of patients

Plasma half-life (hours)

Drug

Number of patients

Plasma half-life (hours)

clonazepam

6

20–60

acetaminophen*

4

4–6

acetaminophen*

5

4–6

celecoxib*

3

10–12

mianserin

2

21–61

diclofenac*

3

3–7

alprazolam

2

12–15

piroxicam*

2

34–50

bromazepam

1

20

clonazepam

1

20–60

triazolam

1

1.5–5.5

alprazolam

1

12–15

piroxicam*

1

34–50

indomethacin*

1

4–5

celecoxib*

1

10–12

aspirin*

1

2–3

ketoprofen*

1

1.5–4

rofecoxib*

1

17

fluoxetine

1

96–144

ibuprofen*

1

2–3

gabapentin*

1

5–9

gabapentin*

1

5–9