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Table 3 Prescribed non-steroidal anti-inflammatory drugs and centrally acting agents. (*) means that the drug was discontinued at least 24 hrs before the study. Plasma half-life of each compound is also indicated.

From: Norepinephrine-evoked pain in fibromyalgia. A randomized pilot study ISCRTN70707830

Fibromyalgia Rheumatoid Arthritis
Drug Number of patients Plasma half-life (hours) Drug Number of patients Plasma half-life (hours)
clonazepam 6 20–60 acetaminophen* 4 4–6
acetaminophen* 5 4–6 celecoxib* 3 10–12
mianserin 2 21–61 diclofenac* 3 3–7
alprazolam 2 12–15 piroxicam* 2 34–50
bromazepam 1 20 clonazepam 1 20–60
triazolam 1 1.5–5.5 alprazolam 1 12–15
piroxicam* 1 34–50 indomethacin* 1 4–5
celecoxib* 1 10–12 aspirin* 1 2–3
ketoprofen* 1 1.5–4 rofecoxib* 1 17
fluoxetine 1 96–144 ibuprofen* 1 2–3
gabapentin* 1 5–9 gabapentin* 1 5–9