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Table 3 Correlations between buspirone challenge test variables and sensoric pain score in female fibromyalgia patients and female population controls.

From: Factors explaining variance in perceived pain in women with fibromyalgia

  Fibromyalgia (N = 22) Controls (N = 13)
Buspirone test variable Correlation with sensoric pain Correlation with sensoric pain
Baseline cortisol -0.43* (p = 0.04) 0.15 (p = 0.61)
Δ Cortisol -0.31 (p = 0.15) 0.37 (p = 0.22)
Baseline systolic blood pressure -0.33 (p = 0.14) 0.43 (p = 0.13)
Δ Systolic blood pressure 0.50* (p = 0.02) -0.31 (p = 0.28)
Baseline diastolic blood pressure -0.26 (p = 0.24) 0.28 (p = 0.33)
Δ Diastolic blood pressure 0.50* (p = 0.02) 0.00 (p = 1.00)
  1. Δ = Level after 90 minutes-baseline level High pain scores are associated with a small drop in blood pressure (Δ systolic blood pressure) after buspirone in fibromyalgia patients. A smaller drop in blood pressure after buspirone gives a smaller negative Δ value, and hence the seen positive correlation.