Table 3 Health-related quality of life assessed using RAND-36 at baseline, one month and 12 months according to treatment group and between group comparisons of difference from baseline to one month and 12 months
Mean (SD) original values | Mean (SD) change | Unadjusted analyses | Adjusted analyses | |||||
|---|---|---|---|---|---|---|---|---|
ZA | Placebo | ZA | Placebo | Difference | P | Difference | P* | |
n = 20 | n = 20 | (95% CI) | (95% CI) | |||||
Total RAND-36 | ||||||||
Baseline | 50 (8) | 50 (7) | ||||||
1 month | 51 (8) | 49 (8) | 0.6 (6.4) | −0.6 (5.0) | 1.2 (−3 to 5) | 0.530 | 1.3 (−3 to 5) | 0.477 |
12 months | 51 (8) | 49 (9) | 1.0 (8.7) | −1.0 (5.9) | 2.1 (−3 to 7) | 0.378 | 2.2 (−2 to 7) | 0.314 |
Physical component | ||||||||
Baseline | 52 (8) | 48 (8) | ||||||
1 month | 52 (9) | 48 (8) | 0.1 (8.6) | −0.1 (5.5) | 0.3 (−4 to 5) | 0.897 | 1.3 (−3 to 6) | 0.554 |
12 months | 52 (8) | 48 (2) | 0.3 (10) | −0.3 (6.5) | 0.7 (−5 to 6) | 0.808 | 2.1 (−3 to 7) | 0.405 |
Mental component | ||||||||
Baseline | 49 (9) | 51 (8) | ||||||
1 month | 50 (9) | 50 (9) | 1.0 (6.1) | −1.0 (5.6) | 2.0 (−2 to 6) | 0.286 | 1.6 (−2 to 5) | 0.396 |
12 months | 51 (9) | 49 (9) | 1.8 (9.0) | −1.8 (6.7) | 3.5 (−2 to 9) | 0.167 | 2.7 (−2 to 7) | 0.261 |