Table 1 Modified mankin scoring criteria
From: Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis
| Â | Score |
|---|---|
Structure | Â |
Normal | 0 |
Surface irregularities | 1 |
Pannus and surface irregularities | 2 |
Clefts to middle zone | 3 |
Clefts to deep zone | 4 |
Clefts to calcified zone | 5 |
Complete disorganization | 6 |
Cells | Â |
Normal | 0 |
Diffuse hypercellularity | 1 |
Cluster/cloning | 2 |
hypocellularity | 3 |
Sarafin O staining | Â |
Normal | 0 |
Slight reduction | 1 |
Moderate reduction | 2 |
Severe reduction | 3 |
No dye noted | 4 |