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Table 1 Summary of the OI patient cohort, medication data, and findings

From: Association between joint hypermobility, scoliosis, and cranial base anomalies in paediatric Osteogenesis imperfecta patients: a retrospective cross-sectional study

  Mild (type I) Moderate (types IV, VI) Severe (type III) Total
Number of patients 30 10 7 47
Age range at skull imaging (years) 1.3-18.1 9.2-18.8 3.8-8.6 1.3-18.8
Mean height Z-score -0.8 -4.0 -5.4 -2.2
Number of patients treated with bisphosphonates 18 8 4 30
Mean duration and range of bisphosphonate treatment prior to imaging (years) 3.6 (0.1-8.3) 3.2 (0.2-10.9) 3.2(2.2-4) 0.7 (0.1-10.9)
Number of patients with hypermobile joints 22 (73%) 6 (60%) 5 (71%) 33 (70%)
Number of patients with scoliosis 3 (10%) 5 (50%) 4 (57%) 12 (26%)
Number of patients with cranial anomaly 2 (6.7%) 5 (50%) 5 (71%) 12 (26%)