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Table 4 Association of MEF2C, SOST and JAG1 polymorphisms with BMD in postmenopausal Mexican-women

From: Analysis of association of MEF2C, SOST and JAG1 genes with bone mineral density in Mexican-Mestizo postmenopausal women

  Gene dbSNP β (95% IC)d p adjust e
BMD-TH a (g/ cm 2 ) MEF2C rs1366594 0.001 (-0.016; 0.017) 0.938
SOST rs9911277 -0.031 (-0.046; -0.016) 0.000072
  rs4793018 -0.027 (-0.043; -0.012) 0.00035
  rs1983490 -0.027 (-0.042; -0.012) 0.00040
  rs1881107 -0.027 (-0.042; -0.011) 0.00055
  rs4792909 -0.025 (-0.040; -0.010) 0.0012
JAG1 rs2273061 0.007 (-0.009; 0.023) 0.409
  rs6040061 0.009 (-0.007; 0.026) 0.280
  rs2235811 0.011 (-0.005; 0.027) 0.189
BMD-FN b (g/ cm 2 ) MEF2C rs1366594 0.004 (-0.011; 0.019) 0.638
SOST rs9911277 -0.029 (-0.043; -0.015) 0.000048
  rs4793018 -0.026 (-0.040; -0.012) 0.00024
  rs1983490 -0.027 (-0.041; -0.013) 0.00018
  rs1881107 -0.026 (-0.040; -0.012) 0.00027
  rs4792909 -0.025 (-0.039; -0.011) 0.00053
JAG1 rs2273061 0.007 (-0.008; 0.022) 0.331
  rs6040061 0.013 (-0.003; 0.028) 0.109
  rs2235811 0.013 (-0.002; 0.028) 0.089
BMD-LS c (g/ cm 2 ) MEF2C rs1366594 0.007 (-0.015; 0.028) 0.542
SOST rs9911277 -0.006 (-0.027; 0.014) 0.539
  rs4793018 -0.007 (-0.027; 0.013) 0.498
  rs1983490 -0.007 (-0.027; 0.014) 0.514
  rs1881107 -0.003 (-0.023; 0.018) 0.806
  rs4792909 -0.002 (-0.022; 0.019) 0.865
JAG1 rs2273061 0.021 (0.000; 0.042) 0.051
  rs6040061 0.008 (-0.014; 0.030) 0.484
  rs2235811 0.007 (-0.015; 0.028) 0.557
  1. aBMD-TH = Total hip bone mineral density.
  2. bBMD-FN = Femoral neck bone mineral density.
  3. cBMD-LS = Lumbar spine bone mineral density.
  4. dData are shown for the additive model.
  5. e p-adjust values were adjusted by age, BMI, and ancestry estimates.