Table 4 Association of MEF2C, SOST and JAG1 polymorphisms with BMD in postmenopausal Mexican-women
Gene | dbSNP | β (95% IC)d | p adjust e | |
|---|---|---|---|---|
BMD-TH a (g/ cm 2 ) | MEF2C | rs1366594 | 0.001 (-0.016; 0.017) | 0.938 |
SOST | rs9911277 | -0.031 (-0.046; -0.016) | 0.000072 | |
rs4793018 | -0.027 (-0.043; -0.012) | 0.00035 | ||
rs1983490 | -0.027 (-0.042; -0.012) | 0.00040 | ||
rs1881107 | -0.027 (-0.042; -0.011) | 0.00055 | ||
rs4792909 | -0.025 (-0.040; -0.010) | 0.0012 | ||
JAG1 | rs2273061 | 0.007 (-0.009; 0.023) | 0.409 | |
rs6040061 | 0.009 (-0.007; 0.026) | 0.280 | ||
rs2235811 | 0.011 (-0.005; 0.027) | 0.189 | ||
BMD-FN b (g/ cm 2 ) | MEF2C | rs1366594 | 0.004 (-0.011; 0.019) | 0.638 |
SOST | rs9911277 | -0.029 (-0.043; -0.015) | 0.000048 | |
rs4793018 | -0.026 (-0.040; -0.012) | 0.00024 | ||
rs1983490 | -0.027 (-0.041; -0.013) | 0.00018 | ||
rs1881107 | -0.026 (-0.040; -0.012) | 0.00027 | ||
rs4792909 | -0.025 (-0.039; -0.011) | 0.00053 | ||
JAG1 | rs2273061 | 0.007 (-0.008; 0.022) | 0.331 | |
rs6040061 | 0.013 (-0.003; 0.028) | 0.109 | ||
rs2235811 | 0.013 (-0.002; 0.028) | 0.089 | ||
BMD-LS c (g/ cm 2 ) | MEF2C | rs1366594 | 0.007 (-0.015; 0.028) | 0.542 |
SOST | rs9911277 | -0.006 (-0.027; 0.014) | 0.539 | |
rs4793018 | -0.007 (-0.027; 0.013) | 0.498 | ||
rs1983490 | -0.007 (-0.027; 0.014) | 0.514 | ||
rs1881107 | -0.003 (-0.023; 0.018) | 0.806 | ||
rs4792909 | -0.002 (-0.022; 0.019) | 0.865 | ||
JAG1 | rs2273061 | 0.021 (0.000; 0.042) | 0.051 | |
rs6040061 | 0.008 (-0.014; 0.030) | 0.484 | ||
rs2235811 | 0.007 (-0.015; 0.028) | 0.557 |