Table 3 The genotype and allele frequencies of SNPs in and around the CHL1 gene in AIS in a Chinese Han population
Genotype | AIS (%) | Control (%) | P-value (χ2) | Alleles | AIS (%) | Control (%) | P-value (χ2) | OR (95% CI) |
|---|---|---|---|---|---|---|---|---|
rs2272524 | ||||||||
CC | 56(30.1) | 43(25.4) | C | 202(54.3) | 169(50.0) | C vs. T | ||
CT | 90(48.4) | 83(49.1) | 0.53 | T | 170(45.7) | 169(50.0) | 0.25 | 1.12 (0.89-1.60) |
TT | 40(21.5) | 43(25.4) | ||||||
rs331894 | ||||||||
GG | 48(25.8) | 39(23.1) | G | 186(50.0) | 170(50.3) | G vs. A | ||
GA | 90(48.4) | 92(54.4) | 0.52 | A | 186(50.0) | 168(49.7) | 0.94 | 0.99 (0.74-1.33) |
AA | 48(25.8) | 38(22.5) | ||||||
rs2272522 | ||||||||
CC | 78(41.9) | 82(48.5) | C | 236(63.4) | 240(71.0) | C vs. T | ||
CT | 80(43.0) | 76(45.0) | 0.03 | T | 136(36.6) | 98(29.0) | 0.03 | 0.71 (0.52-0.97) |
TT | 28(15.1) | 11(6.5) | ||||||
rs2055314 | ||||||||
CC | 59(31.7) | 34(20.1) | C | 199(53.5) | 150(44.4) | C vs. T | ||
CT | 81(43.5) | 82(48.5) | 0.04 | T | 173(46.5) | 188(55.6) | 0.02 | 1.44 (1.07-1.94) |
TT | 46(24.7) | 53(31.4) | ||||||
rs10510181 | ||||||||
GG | 57(30.6) | 36(21.3) | G | 199(53.5) | 152(45.0) | G vs. A | ||
GA | 85(45.7) | 80(47.3) | 0.08 | A | 173(46.5) | 186(55.0) | 0.02 | 1.41 (1.05-1.89) |
AA | 44(23.7) | 53(31.4) |