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Figure 4 | BMC Musculoskeletal Disorders

Figure 4

From: Effects of pamidronate disodium on the loss of osteoarthritic subchondral bone and the expression of cartilaginous and subchondral osteoprotegerin and RANKL in rabbits

Figure 4

Assessment of articular cartilage changes according to the 2010 OARSI recommendations in the rabbit. The score represents the sum of the scores of staining, structure, chondrocyte density and cluster formation. A significant increase of OARSI scores in the ACLT group can be observed with time, and PAM can prevent and lower the increase in the OA scores, compared with the ACLT group at 4 weeks. *P <0.05, **P <0.01, # indicates group significantly different from the sham-operated rabbits treated with vehicle (# P <0.05 and ## P <0.01).

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