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Table 5 Association of haplotypes with hand OA

From: Variations in the TNFα gene and their interactions with the IL4R and IL10 genes in relation to hand osteoarthritis

  OA- (n = 382) OA + (n = 160) OR (95% CI) p-value
TNFα-1031-863 -308     0.07*
T-C-G 0.71 0.65 1.00  
C-A-G 0.14 0.19 1.61 (1.10-2.37) 0.01
T-C-A 0.13 0.15 1.35 (0.89-2.03) 0.16
C-C-G 0.02 0.02 0.93 (0.33-2.58) 0.88
IL4R     0.65*
Ser-Ser 0.88 0.86 1.00  
Ser-Pro 0.10 0.10 1.08 (0.67-1.74) 0.73
Ala-Pro 0.02 0.04 1.43 (0.67-3.03) 0.37
  1. ORs and their 95% CIs were adjusted for age, occupation and BMI.
  2. *Global haplotype association p-value.