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Table 5 Association of haplotypes with hand OA

From: Variations in the TNFα gene and their interactions with the IL4R and IL10 genes in relation to hand osteoarthritis

 

OA- (n = 382)

OA + (n = 160)

OR (95% CI)

p-value

TNFα-1031-863 -308

   

0.07*

T-C-G

0.71

0.65

1.00

 

C-A-G

0.14

0.19

1.61 (1.10-2.37)

0.01

T-C-A

0.13

0.15

1.35 (0.89-2.03)

0.16

C-C-G

0.02

0.02

0.93 (0.33-2.58)

0.88

IL4R

   

0.65*

Ser-Ser

0.88

0.86

1.00

 

Ser-Pro

0.10

0.10

1.08 (0.67-1.74)

0.73

Ala-Pro

0.02

0.04

1.43 (0.67-3.03)

0.37

  1. ORs and their 95% CIs were adjusted for age, occupation and BMI.
  2. *Global haplotype association p-value.
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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