Figure 4

GLPG0492 increased plasma metabolite levels linked to TCA cycle, β - oxidation and amino acids metabolism. Metabolic profiling by 1H-NMR of serum samples from intact or immobilized mice receiving either GLPG0492 (10 mg/kg/day) or vehicle was performed at day 7. (n = 5 per group; #p < 0.05 Intact vs. Immobilized; *p < 0.05, **p < 0.01 vs. CTL immobilized).