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Table 7 Osteopathic manipulative treatment in comparison to usual obstetric care, sham ultrasound and untreated for nonspecific low back pain in pregnant women

From: Osteopathic manipulative treatment for nonspecific low back pain: a systematic review and meta-analysis

Quality assessment

No. of patients

Treatment effect (95% CI)

Quality of the evidence

No. of studies

Design

Limitations

Inconsistency

Indirectness

Imprecision

Other considerations

OMT

Usual obstetric care, sham ultrasound and untreated

Pain (measured with: Pain VAS from 0 to 100 [worse pain]; Better indicated by lower values)

3

randomised trials

no serious limitations

serious1

no serious indirectness

serious2

none

99

143

MD 23.01 lower (44.13 to 1.88 lower)

⊕ ⊕ ΟΟ LOW

Functional status (measured with: Roland-Morris Disability Questionnaire, Quebec Back Pain Disability Scale; Better indicated by lower values)

3

randomised trials

no serious limitations

serious3

no serious indirectness

serious2

none

99

143

SMD 0.80 lower (1.36 to 0.23 lower)

⊕ ⊕ ΟΟ LOW

  1. 1I2 = 91%.
  2. 2Sample size < 400.
  3. 3I2 = 76%.
  4. Abbreviations: CI Confidence interval, MD Mean difference, OMT Osteopathic manipulative treatment, SMD Standard mean difference, VAS Visual analogue scale.