BMC Musculoskeletal Disorders

Table 2 KIR gene distribution and its effect on MTX response

From: Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment

MTX response	KIR genes
	2DS2	2DL3	2DL2	2DS3	2DL1	3DL1	3DS1	2DS5	2DS1	2DS4f*	2DS4d
Good responders (N = 179)
Presence (N)	107	155	103	68	178	171	59	52	71	55	156
Absence (N)	7	24	76	111	21	8	120	127	108	124	23
Frequency [%]	59.78	86.59	57.54	37.99	99.44	95.53	32.96	29.05	39.66	30.73	87.15
Poor responders (N = 133)
Presence (N)	75	121	71	33	129	121	46	41	55	50	110
Absence (N)	5	12	62	100	84	12	87	92	78	83	23
Frequency [%]	56.39	90.98	53.38	24.81	96.99	90.98	34.59	30.83	41.35	37.59	82.71

*Good responders vs poor responders: p = 0.0334; OR = 0.43, 95%CI = 0.215-0.987.

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ISSN: 1471-2474

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