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Table 2 Estimated study power for 750 patients per treatment arm (N = 1500)

From: Fixation using alternative implants for the treatment of hip fractures (FAITH): design and rationale for a multi-centre randomized trial comparing sliding hip screws and cancellous screws on revision surgery rates and quality of life in the treatment of femoral neck fractures

Baseline risk

(Year 1)^

Relative risk reduction

 

10%

15%

20%

25%

30%

20%

15.9%

30.8%

50.5%

70.5%

86.1%

25%

19.6%

38.7%

61.6%

81.5%

93.5%

30%

23.6%

46.8%

71.7%

89.3%

97.4%

35%

28.2%

55.2%

80.3%

94.5%

99.1%

40%

33.3%

63.6%

87.3%

97.5%

99.7%

  1. *Number of patients per treatment arm, alpha = 0.05.
  2. ^Year 2 risk is 1/3 that of year 1.
  3. Bold numbers indicate statistical power range for this study.