Table 6 Haplotype analysis of the three identified SNPs in FN-1 between OA cases and control subjects in both studies
Haplotype | Frequencies | p | OR (95% CI) | |||
|---|---|---|---|---|---|---|
rs940739 | rs2304573 | rs11651 | Case | Control | ||
A | G | A | 0.581 | 0.597 | 0.386 | 0.94 (0.82-1.08) |
T | G | G | 0.130 | 0.127 | 0.771 | 1.03 (0.84-1.27) |
A | G | G | 0.095 | 0.099 | 0.729 | 0.96 (0.76-1.21) |
A | A | G | 0.066 | 0.101 | < 0.001 | 0.63 (0.49-0.81) |
T | G | A | 0.047 | 0.024 | < 0.001 | 2.03 (1.35-3.06) |
A | A | A | 0.031 | 0.022 | 0.087 | 1.47 (0.94-2.30) |
T | G | G | 0.027 | 0.021 | 0.289 | 1.28 (0.81-2.03) |
T | A | A | 0.022 | 0.010 | 0.013 | 2.12 (1.16-3.89) |