Variables | Study 1 | Study 2 | Study 1 + Study 2 | ||||
---|---|---|---|---|---|---|---|
Case (%) | Control (%) | Case (%) | Control (%) | Case (%) | Control (%) | p | |
Number | 403 | 314 | 525 | 379 | 928 | 693 | |
Age (mean ± SD) | 72.54 ± 8.13 | 69.34 ± 9.80 | 72.18 ± 8.12 | 69.87 ± 9.96 | 72.34 ± 8.13 | 69.63 ± 9.88 | < 0.001 |
Gender (% Female) | 65.4% | 53.8% | 65.6% | 58.6% | 65.5% | 56.4% | < 0.001 |
BMI (mean ± SD) | 25.28 ± 3.13 | 24.95 ± 9.88 | 25.08 ± 3.16 | 24.26 ± 3.79 | 25.17 ± 3.15 | 24.57 ± 7.22 | 0.04 |
K-L grading (%) | |||||||
Grade 0 | 0 | 162 (51.60) | 0 | 189 (49.87) | 0 | 351 (50.65) | |
Grade 1 | 0 | 152 (48.40) | 0 | 190 (50.13) | 0 | 342 (49.35) | |
Grade 2 | 146 (36.23) | 0 | 205 (39.05) | 0 | 351 (37.82) | 0 | |
Grade 3 | 73 (18.11) | 0 | 74 (14.10) | 0 | 147 (15.84) | 0 | |
Grade 4 | 184 (45.66) | 0 | 246 (46.85) | 0 | 430 (46.34) | 0 |