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Table 1 Characteristics of OA cases and healthy controls

From: An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case- control studies

Variables

Study 1

 

Study 2

 

Study 1 + Study 2

 

Case (%)

Control (%)

Case (%)

Control (%)

Case (%)

Control (%)

p

Number

403

314

525

379

928

693

 

Age (mean ± SD)

72.54 ± 8.13

69.34 ± 9.80

72.18 ± 8.12

69.87 ± 9.96

72.34 ± 8.13

69.63 ± 9.88

< 0.001

Gender (% Female)

65.4%

53.8%

65.6%

58.6%

65.5%

56.4%

< 0.001

BMI (mean ± SD)

25.28 ± 3.13

24.95 ± 9.88

25.08 ± 3.16

24.26 ± 3.79

25.17 ± 3.15

24.57 ± 7.22

0.04

K-L grading (%)

       

Grade 0

0

162 (51.60)

0

189 (49.87)

0

351 (50.65)

 

Grade 1

0

152 (48.40)

0

190 (50.13)

0

342 (49.35)

 

Grade 2

146 (36.23)

0

205 (39.05)

0

351 (37.82)

0

 

Grade 3

73 (18.11)

0

74 (14.10)

0

147 (15.84)

0

 

Grade 4

184 (45.66)

0

246 (46.85)

0

430 (46.34)

0