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Table 4 Protein levels and OCD stage

From: Association between intraarticular cytokine levels and clinical parameters of osteochondritis dissecans in the ankle

  OCD grading FFI (reverse) CFSS AOFAS KLS AOSS
MMP-13/MMP-13/TPC
 Correlation -/- -/- -/- -/- -/- -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s.
IL-1β/IL-1β/TPC
 Correlation neg. / - - / - - / - -/- -/- -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) 0.040/n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s.
bFGF/bFGF/TPC
 Correlation -/- -/- -/- -/- -/pos. -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./0.050 n.s./n.s.
BMP-2/BMP-2/TPC
 Correlation -/- -/- -/- -/- -/- -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s.
BMP-7/BMP-7/TPC
 Correlation -/- -/- -/- -/- pos./- -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) n.s. / n.s. n.s. / n.s. n.s. / n.s. n.s./n.s. 0.050/n.s. n.s./n.s.
Endoglin/Endoglin/TPC
 Correlation -/- neg./- pos./- -/- -/- -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) n.s./n.s. 0.038/n.s. 0.015/- n.s./n.s. n.s./n.s. n.s./n.s.
IGF-1/IGF-1/TPC
 Correlation neg./- neg./- pos./pos. pos./- -/- -/-
 Valid cases 28 28 28 28 28 25
 Signif. (P) 0.018/n.s. 0.032/n.s. 0.001 / 0.021 0.030/n.s. n.s./n.s. n.s./n.s.
IGF-1R/IGF-1R/TPC
 Correlation neg./neg. neg./- -/- -/- neg./neg. neg./-
 Valid cases 28 28 28 28 28 25
 Signif. (P) 0.004/0.012 0.045/n.s. n.s./n.s. n.s./n.s. 0.001 / 0.005 0.006/n.s.
Aggrecan/Aggrecan/TPC
 Correlation -/- -/- -/- -/- -/- -/pos.
 Valid cases 28 28 28 28 28 25
 Signif. (P) n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./n.s. n.s./0.048
  1. Correlation of intraarticular protein levels of patients with OCD with OCD stage according to Berndt and Harty, functional scores and OA-related changes in conventional X-ray or MRI, signif. (P): p-value for statistical significance Spearman’s ρ, FFI: foot function index, CFSS: calcaneal fractures scoring system according to Kerr, AOFAS: ankle-hindfoot scale, KLS: Kellgren Lawrence Score, AOSS: ankle osteoarthritis scoring system, TPC: total protein content. Statistical tests refer to correlations to the absolute protein concentrations and the protein concentrations in relation to TPC.