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Table 4 Protein levels and OCD stage

From: Association between intraarticular cytokine levels and clinical parameters of osteochondritis dissecans in the ankle

 

OCD grading

FFI (reverse)

CFSS

AOFAS

KLS

AOSS

MMP-13/MMP-13/TPC

 Correlation

-/-

-/-

-/-

-/-

-/-

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

IL-1β/IL-1β/TPC

 Correlation

neg. / -

- / -

- / -

-/-

-/-

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

0.040/n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

bFGF/bFGF/TPC

 Correlation

-/-

-/-

-/-

-/-

-/pos.

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./0.050

n.s./n.s.

BMP-2/BMP-2/TPC

 Correlation

-/-

-/-

-/-

-/-

-/-

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

BMP-7/BMP-7/TPC

 Correlation

-/-

-/-

-/-

-/-

pos./-

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

n.s. / n.s.

n.s. / n.s.

n.s. / n.s.

n.s./n.s.

0.050/n.s.

n.s./n.s.

Endoglin/Endoglin/TPC

 Correlation

-/-

neg./-

pos./-

-/-

-/-

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

n.s./n.s.

0.038/n.s.

0.015/-

n.s./n.s.

n.s./n.s.

n.s./n.s.

IGF-1/IGF-1/TPC

 Correlation

neg./-

neg./-

pos./pos.

pos./-

-/-

-/-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

0.018/n.s.

0.032/n.s.

0.001 / 0.021

0.030/n.s.

n.s./n.s.

n.s./n.s.

IGF-1R/IGF-1R/TPC

 Correlation

neg./neg.

neg./-

-/-

-/-

neg./neg.

neg./-

 Valid cases

28

28

28

28

28

25

 Signif. (P)

0.004/0.012

0.045/n.s.

n.s./n.s.

n.s./n.s.

0.001 / 0.005

0.006/n.s.

Aggrecan/Aggrecan/TPC

 Correlation

-/-

-/-

-/-

-/-

-/-

-/pos.

 Valid cases

28

28

28

28

28

25

 Signif. (P)

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./n.s.

n.s./0.048

  1. Correlation of intraarticular protein levels of patients with OCD with OCD stage according to Berndt and Harty, functional scores and OA-related changes in conventional X-ray or MRI, signif. (P): p-value for statistical significance Spearman’s ρ, FFI: foot function index, CFSS: calcaneal fractures scoring system according to Kerr, AOFAS: ankle-hindfoot scale, KLS: Kellgren Lawrence Score, AOSS: ankle osteoarthritis scoring system, TPC: total protein content. Statistical tests refer to correlations to the absolute protein concentrations and the protein concentrations in relation to TPC.