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Table 2 Non-responder characteristics

From: Depression in primary TKA and higher medical comorbidities in revision TKA are associated with suboptimal subjective improvement in knee function

 

2-yr primary TKA

5-yr primary TKA

2-yr revision TKA

5-yr revision TKA

 

Events for non-responders (3818/ 10957)

OR (95%)) CI)

Events for non-responders (3170/7404)

OR (95%)) CI)

Events for non-responders (1162/2695)

OR (95%)) CI)

Events for non-responders (961/1842)

OR (95%)) CI)

Gender

        

 Women

2184/6161 (35.4%)

 

1860/4191 (44.4%)

 

621/1402 (44.3%)

 

509/944 (53.9%)

 

 Men

1634/4796 (34.1%)

0.94 (0.86,1.03)

1310/3213 (40.8%)

0.86 ‡ (0.78,0.96)

541/1293 (41.8%)

1.10 (0.94, 1.29)

452/898 (50.3%)

0.87 (0.72,1.05)

Age groups n (%)

        

 ≤60 yrs

841/2154 (39%)

 

728/1473 (49.4%)

 

283/587 (48.2%)

 

241/413 (58.4%)

 

 >60-70 yrs

1273/3804 (33.5%)

0.79 ‡ (0.69,0.89)

1065/2641 (40.3%)

0.69 ‡ (0.60,0.80)

365/816 (44.7%)

0.87 (0.70,1.08)

281/555 (50.6%)

0.73* (0.56,0.96)

 >70-80 yrs

1387/4121 (33.7%)

0.79 ‡ (0.70,0.89)

1142/2759 (41.4%)

0.72 ‡ (0.63,0.83)

391/1034 (37.8%)

0.65‡ (0.53,0.81)

350/714 (49%)

0.69 ‡ (0.53,0.89)

 >80 yrs

317/878 (36.1%)

0.88 (0.74,1.05)

235/531 (44.3%)

0.81 (0.65,1.01)

123/258 (47.7%)

0.98 (0.72,1.32)

89/160 (55.6%)

0.89 (0.61,1.31)

BMI Categorized

        

 ≤24.9

514/1474 (34.9%)

 

452/1018 (44.4%)

 

172/375 (45.9%)

 

136/258 (52.7%)

 

 25-29.9

1287/3766 (34.2%)

0.97 (0.84,1.11)

1061/2586 (41%)

0.87 (0.74,1.02)

375/925 (40.5%)

0.80 (0.63,1.03)

310/655 (47.3%)

0.81 (0.60,1.09)

 30-39.9

1644/4712 (34.9%)

1.00 (0.87,1.15)

1346/3169 (42.5%)

0.92 (0.79,1.08)

485/1149 (42.2%)

0.86 (0.68,1.09)

423/784 (54%)

1.05 (0.79,1.41)

 ≥40

355/960 (37%)

1.10 (0.91,1.32)

299/602 (49.7%)

1.24 (0.99,1.55)

123/229 (53.7%)

1.37 (0.98,1.91)

89/136 (65.4%)

1.70* (1.09,2.66)

ASA

        

 1-2

2021/6136 (32.9%)

 

1771/4238 (41.8%)

 

505/1270 (39.8%)

 

432/899 (48.1%)

 

 3-4

1772/4778 (37.1%)

1.20 ‡ (1.10,1.31)

1388/3129 (44.4%)

1.11* (1.00,1.23)

651/1414 (46%)

1.29 ‡ (1.10,1.51)

523/933 (56.1%)

1.38 ‡ (1.15,1.66)

Deyo-Charlson index (5 point increase)

 

1.30 ‡ (1.17,1.44)

 

1.07 (0.93,1.22)

 

1.16 (0.93,1.44)

 

1.63 ‡ (1.21,2.20)

Income

        

 >$45 K

1035/3099 (33.4%)

 

720/1665 (43.2%)

 

236/548 (43.1%)

 

163/304 (53.6%)

 

 ≤$35 K

699/2098 (33.3%)

1.00 (0.87,1.14)

736/1841 (40%)

0.87 (0.75,1.02)

254/595 (42.7%)

1.98 (0.77,1.25)

243/488 (49.8%)

0.86 (0.64, 1.15)

 >$35 K-$45 K

1347/4044 (33.3%)

1.00 (0.89,1.11)

1058/2541 (41.6%)

0.94 (0.82,1.07)

450/1050 (42.9%)

0.99 (0.80,1.23)

363/677 (53.6%)

1.00 (0.76,1.32)

Distance

        

 0-100 miles

1785/5454 (32.7%)

 

1443/3523 (41%)

 

390/865 (45.1%)

 

284/571 (49.7%)

 

 >100-500 miles

1435/4166 (34.4%)

1.08 (0.98,1.19)

1218/2871 (42.4%)

1.06 (0.95,1.19)

602/1449 (41.5%)

0.87 (0.72,1.03)

535/993 (53.9%)

1.18 (0.95, 1.46)

 >500 miles or Non-US

476/1017 (46.8%)

1.81 ‡ (1.55,2.11)

382/709 (53.9%)

1.68 ‡ (1.40,2.03)

129/293 (44%)

0.96 (0.73,1.27)

103/200 (51.5%)

1.07 (0.77, 1.50)

Underlying diagnoses

        

 Inflammatory arthritis

172/428 (40.2%)

 

155/344 (45.1%)

     

 Osteoarthritis

3480/10190(34.2%)

0.77* (0.62,0.97)

2872/6794 (42.3%)

0.89 (0.70,1.14)

    

 Other

166/338 (49.1%)

1.44* (1.05,1.96)

143/266 (53.8%)

1.42* (1.00,2.01)

    

 Loosening/wear or osteolysis

    

584/1453 (40.2%)

 

475/1015 (46.8%)

 

 Dislocation, bone or prosthesis fracture, instability, non-union

    

254/597 (42.5%)

1.10 (0.91,1.34)

216/393 (55%)

1.39 ‡ (1.10,1.76)

 Failed prior arthroplasty with components removed or infection

    

324/645 (50.2%)

1.50‡ (1.24,1.82)

270/434 (62.2%)

1.87 ‡ (1.48,2.36)

  1. *P < 0.05; ‡p < 0.01, †p < 0.001.
  2. All other p-values are ≥0.05, unless indicated as above.
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