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Table 2 Non-responder characteristics

From: Depression in primary TKA and higher medical comorbidities in revision TKA are associated with suboptimal subjective improvement in knee function

  2-yr primary TKA 5-yr primary TKA 2-yr revision TKA 5-yr revision TKA
  Events for non-responders (3818/ 10957) OR (95%)) CI) Events for non-responders (3170/7404) OR (95%)) CI) Events for non-responders (1162/2695) OR (95%)) CI) Events for non-responders (961/1842) OR (95%)) CI)
Gender         
 Women 2184/6161 (35.4%)   1860/4191 (44.4%)   621/1402 (44.3%)   509/944 (53.9%)  
 Men 1634/4796 (34.1%) 0.94 (0.86,1.03) 1310/3213 (40.8%) 0.86 (0.78,0.96) 541/1293 (41.8%) 1.10 (0.94, 1.29) 452/898 (50.3%) 0.87 (0.72,1.05)
Age groups n (%)         
 ≤60 yrs 841/2154 (39%)   728/1473 (49.4%)   283/587 (48.2%)   241/413 (58.4%)  
 >60-70 yrs 1273/3804 (33.5%) 0.79 (0.69,0.89) 1065/2641 (40.3%) 0.69 (0.60,0.80) 365/816 (44.7%) 0.87 (0.70,1.08) 281/555 (50.6%) 0.73* (0.56,0.96)
 >70-80 yrs 1387/4121 (33.7%) 0.79 (0.70,0.89) 1142/2759 (41.4%) 0.72 (0.63,0.83) 391/1034 (37.8%) 0.65 (0.53,0.81) 350/714 (49%) 0.69 (0.53,0.89)
 >80 yrs 317/878 (36.1%) 0.88 (0.74,1.05) 235/531 (44.3%) 0.81 (0.65,1.01) 123/258 (47.7%) 0.98 (0.72,1.32) 89/160 (55.6%) 0.89 (0.61,1.31)
BMI Categorized         
 ≤24.9 514/1474 (34.9%)   452/1018 (44.4%)   172/375 (45.9%)   136/258 (52.7%)  
 25-29.9 1287/3766 (34.2%) 0.97 (0.84,1.11) 1061/2586 (41%) 0.87 (0.74,1.02) 375/925 (40.5%) 0.80 (0.63,1.03) 310/655 (47.3%) 0.81 (0.60,1.09)
 30-39.9 1644/4712 (34.9%) 1.00 (0.87,1.15) 1346/3169 (42.5%) 0.92 (0.79,1.08) 485/1149 (42.2%) 0.86 (0.68,1.09) 423/784 (54%) 1.05 (0.79,1.41)
 ≥40 355/960 (37%) 1.10 (0.91,1.32) 299/602 (49.7%) 1.24 (0.99,1.55) 123/229 (53.7%) 1.37 (0.98,1.91) 89/136 (65.4%) 1.70* (1.09,2.66)
ASA         
 1-2 2021/6136 (32.9%)   1771/4238 (41.8%)   505/1270 (39.8%)   432/899 (48.1%)  
 3-4 1772/4778 (37.1%) 1.20 (1.10,1.31) 1388/3129 (44.4%) 1.11* (1.00,1.23) 651/1414 (46%) 1.29 (1.10,1.51) 523/933 (56.1%) 1.38 (1.15,1.66)
Deyo-Charlson index (5 point increase)   1.30 (1.17,1.44)   1.07 (0.93,1.22)   1.16 (0.93,1.44)   1.63 (1.21,2.20)
Income         
 >$45 K 1035/3099 (33.4%)   720/1665 (43.2%)   236/548 (43.1%)   163/304 (53.6%)  
 ≤$35 K 699/2098 (33.3%) 1.00 (0.87,1.14) 736/1841 (40%) 0.87 (0.75,1.02) 254/595 (42.7%) 1.98 (0.77,1.25) 243/488 (49.8%) 0.86 (0.64, 1.15)
 >$35 K-$45 K 1347/4044 (33.3%) 1.00 (0.89,1.11) 1058/2541 (41.6%) 0.94 (0.82,1.07) 450/1050 (42.9%) 0.99 (0.80,1.23) 363/677 (53.6%) 1.00 (0.76,1.32)
Distance         
 0-100 miles 1785/5454 (32.7%)   1443/3523 (41%)   390/865 (45.1%)   284/571 (49.7%)  
 >100-500 miles 1435/4166 (34.4%) 1.08 (0.98,1.19) 1218/2871 (42.4%) 1.06 (0.95,1.19) 602/1449 (41.5%) 0.87 (0.72,1.03) 535/993 (53.9%) 1.18 (0.95, 1.46)
 >500 miles or Non-US 476/1017 (46.8%) 1.81 (1.55,2.11) 382/709 (53.9%) 1.68 (1.40,2.03) 129/293 (44%) 0.96 (0.73,1.27) 103/200 (51.5%) 1.07 (0.77, 1.50)
Underlying diagnoses         
 Inflammatory arthritis 172/428 (40.2%)   155/344 (45.1%)      
 Osteoarthritis 3480/10190(34.2%) 0.77* (0.62,0.97) 2872/6794 (42.3%) 0.89 (0.70,1.14)     
 Other 166/338 (49.1%) 1.44* (1.05,1.96) 143/266 (53.8%) 1.42* (1.00,2.01)     
 Loosening/wear or osteolysis      584/1453 (40.2%)   475/1015 (46.8%)  
 Dislocation, bone or prosthesis fracture, instability, non-union      254/597 (42.5%) 1.10 (0.91,1.34) 216/393 (55%) 1.39 (1.10,1.76)
 Failed prior arthroplasty with components removed or infection      324/645 (50.2%) 1.50 (1.24,1.82) 270/434 (62.2%) 1.87 (1.48,2.36)
  1. *P < 0.05; p < 0.01, p < 0.001.
  2. All other p-values are ≥0.05, unless indicated as above.